Buch, Englisch, 100 Seiten, Format (B × H): 155 mm x 235 mm, Gewicht: 195 g
Buch, Englisch, 100 Seiten, Format (B × H): 155 mm x 235 mm, Gewicht: 195 g
Reihe: Research and Perspectives in Alzheimer's Disease
ISBN: 978-3-642-72105-2
Verlag: Springer
The role of the familial Alzheimer's Disease genes called "presenilins" in causing neuronal cell death and Alzheimer-related pathology.
Zielgruppe
Research
Autoren/Hrsg.
Weitere Infos & Material
Molecular Genetics of the Presenilins in Alzheimer’s Disease.- Alzheimer’s Disease: A Matter of Dominance.- Alternative Endoproteolysis of the Presenilins and Familial Alzheimer’s Disease.- The APP and PS1/2 Mutations Linked to Early Onset Familial Alzheimer’s Disease Increase the Extracellular Concentration of A?1-42(43).- Metabolism and Function of Presenilin 1.- Mechanistic Studies of the Effect of Presenilins 1 and 2 on APP Metabolism.- Presenilin 2 — APP Interactions.- The Cellular Biology of Presenilin Proteins and a Novel Mechanism of Amyloid ?-Peptide Generation.- Regulation of Presenilin 1 Phosphorylation and Transcriptional Activation of Signal Transduction-Induced Genes by Muscarinic Receptors.- Neuronal Regulation of Presenilin-1 Processing.- Transgenic Approaches to the Study of Alzheimer’s Disease.
