Urban | Vertical 2: The Next Level of Hard and Soft Tissue Augmentation | E-Book | sack.de
E-Book

E-Book, Englisch, 560 Seiten

Urban Vertical 2: The Next Level of Hard and Soft Tissue Augmentation

E-Book, Englisch, 560 Seiten

ISBN: 978-3-86867-592-4
Verlag: Quintessenz
Format: EPUB
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)



In the author's bestselling first book, Vertical and Horizontal Ridge Augmentation: New Perspectives, published by Quintessence in 2017 and translated into 12 languages, the guided bone regeneration (GBR) technique was described in detail. This new publication, Vertical 2: The Next Level of Hard and Soft Tissue Augmentation, is a continuation of that book but at a more advanced level. Now, the author delves into the details where the devil lives, and shares information that has never been revealed before on the topic of vertical ridge augmentation. It is important to read this book armed with the knowledge from the first book as you will need it on this second journey with him.

A major part of this book comprises full-color, step-by-step images of patient cases. At times, reading it is like watching a surgical video, where the author 'stops the video' to discuss with you, the reader, what he is thinking and doing at that step, what his next step will be, and the reason for it.

Included again are the well-appreciated 'Lessons learned' sections, where the learning objectives are emphasized and further notes given, including ways to further improve the techniques. The section on the mandible is more detailed in this book, with the focus on larger defects and the different surgical steps in native, fibrotic, and scarred tissue types around the mental nerve during flap advancement.

In addition, light is shed on the detail in treating the anterior maxilla, which has not been published previously. It includes treatment options such as the fast track, the safe track, and the technical track of soft tissue reconstruction in conjunction with bone grafting as well as papilla reconstructions after bone regeneration. The section on the posterior maxilla hopes to resolve issues such as the management and complications of combined ridge and sinus grafting, including difficulties such as the lack of buccal, crestal or nasal bony walls of the posterior maxilla before bone grafting.

In this must-have new publication, the procedures are kept simple, repeatable, and biologically sound. The techniques presented are not overcomplicated; they are simple treatment strategies with lower complication rates and more predictability in the final outcome.
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Contents
Chapter 01. The biology of vertically and horizontally augmented bone
Chapter 02. Scientific evidence of vertical bone augmentation utilizing a titanium-reinforced polytetrafluoroethylene mesh

The extreme vertical defect of the posterior mandible
Chapter 03. Reconstruction of the extreme posterior mandibular defect: surgical principles and anatomical considerations
Chapter 04. Reconstruction of an advanced posterior mandibular defect with scarred tissue
Chapter 05. Reconstruction of an advanced posterior mandibular defect with narrow basal bone
Chapter 06. Reconstruction of an advanced posterior mandibular defect with incomplete periodontal bone levels: the 'pawn sacrifice'
Chapter 07. Reconstruction of an advanced posterior mandibular defect with the Lasagna technique using low-dose bone morphogenetic protein-2

Anterior mandibular vertical augmentation
Chapter 08. Reconstruction of the advanced anterior mandibular defect: surgical principles and anatomical considerations
Chapter 09. Reconstruction of the advanced anterior mandibular defect: considerations for soft tissue reconstruction and preservation of the regenerated bone
Chapter 10. Reconstruction of the advanced anterior mandibular defect: importance of horizontal bone gain

Posterior maxilla
Chapter 13. Difficulties in sinus augmentation and posterior maxillary reconstructions: missing labial sinus wall and ridge deficiencies
Chapter 14. Sinus graft infection and postoperative sinusitis
Chapter 15. The reconstruction of an extreme vertical defect in the posterior maxilla

Anterior maxillary vertical augmentation
Chapter 16. Introduction and clinical treatment guidelines
Chapter 17. Complex reconstruction of an anterior maxillary vertical defect

Extreme defect
Chapter 18. Anterior maxillary extreme defect augmentation

Soft tissue reconstruction in conjunction with bone grafting
Chapter 19. Reconstruction of a natural soft tissue architecture after bone regeneration
Chapter 20. The labial strip gingival graft
Chapter 21. The double strip graft
Chapter 22. Large open-healing connective tissue graft

Reconstruction of the interimplant papilla
Chapter 23. The double connective tissue graft
Chapter 24. The Ice-cube connective tissue graft
Chapter 25. The Iceberg connective tissue graft

Interproximal bone and soft tissue regeneration
Chapter 26. Vertical periodontal regeneration in combination with ridge augmentation

Ultimate esthetics
Chapter 27. Ultimate esthetics: reconstruction of the bone and soft tissue in conjunction with preserving the mucogingival junction

Complications
Chapter 28. Complications


Introduction
1
The biology of vertically and horizontally augmented bone
Vertical bone growth is very challenging, both biologically and technically. A recent meta-analysis by Urban et al1 found that, regardless of the technique, about 4.5 mm of vertical bone gain was achieved in the included studies. However, complications occur least frequently when the guided bone regeneration (GBR) technique is used. The results of this study indicate the advantage of using GBR. The technical challenge of GBR is discussed extensively in this book, while the biologic challenge that may play a role in limiting vertical bone gain is discussed in this chapter. Based on the author’s experience, the amount of vertical bone gain is not limited by biology, but more by the clinician’s abilities. The biologic background of vertical bone gain was investigated by the author in preclinical settings. The histology of polytetrafluoroethylene (PTFE) membranes in an in vivo setting
The mucogingival tissue is primarily characterized by a moderate vascularized fibrotic reaction that surrounds the PTFE membrane. The membrane is usually internally and externally surrounded by connective tissue that is rich in fibers and poor in cells, with the fibers oriented parallel to the membrane. Membrane pores, if present, show the presence of a highly vascularized matrix of connective tissue and a dense network of collagen fibers that penetrates across the pores to fix on the internal side of the membrane or, in some cases, to the newly formed bone. The inner layer, which is composed of expanded PTFE (e-PTFE), is always placed against the bone of the lingual and buccal sides. A slight number of macrophages admixed with a few lymphocytes, polymorphonuclear cells, giant cells/osteoclasts, and plasma cells were observed around the membrane. Deep at the lingual side of the ridge, the membrane was often in direct contact with the bone tissue, even showing slight signs of osteointegration (Figs 1-1 to 1-4). Figs 1-1 and 1-2 Parallel-oriented fibers around the membranes. Fig 1-3 The membrane shows signs of osseointegration on both sides. Note the excellent biocompatibility of the polytetrafluoroethylene (PTFE) membrane. Fig 1-4 When compared with titanium, the PTFE-membrane demonstrated similar biocompatibility. Figs 1-5 and 1-6 Histologic results of vertical augmentation. Note the excellent new bone formation and the well-incorporated xenograft particles. Bone growth using a xenogenic bone graft In a preclinical in vivo setting, a chronic vertical defect was treated using a xenograft. After 17 weeks of healing, the following was found: Emerging from the defect bed, the bone growth of a moderate to marked amount showed similar signs of remodeling, resulting in significant vertical ridge augmentation. The bone filler was markedly osteointegrated, showed slight signs of degradation, and demonstrated definite signs of osteoconduction (bone growth on the surface of the granules). The newly formed bone harbored numerous osteoblasts (Figs 1-5 and 1-6). The epifluorescence analysis showed a marked grade of mineralization activity at different time points (OTC and XO), respectively. The signs of mineralization activity were visible at the newly formed and remodeled harversian systems (numerous concentric labeled rings). The outer circumferential bone lamellae were not fully formed, as is shown by their irregular shape. Two distinct and spaced lines of labeling (first OTC, then XO) indicated a marked vertical bone growth (Figs 1-7 to 1-10). Figures 1-9 and 1-10 show that the xenograft particles are well incorporated in the newly formed trabecular bone. These images also demonstrate the phases of bone formation and maturation. In the first phase, the newly formed ridge is present, but the cortical bone and the lacunae are not fully developed. This is referred to as ‘baby bone’ (Figs 1-11 and 1-12). Figs 1-7 and 1-8 Epifluorescence analysis of a well-developed and mature bone after vertical augmentation. In the next phase, the bone starts to further mature and corticalize, after which the outer layer becomes smooth and gains its final shape. Although the bone was good enough for the placement of implants, it would need about 3 more months to fully develop. Figs 1-9 and 1-10 Epifluorescence analysis demonstrating the haversian canals and the cortical bone formation of the newly formed bone. The images demonstrate the incorporation of a biomaterial into the newly formed bone and the different time points of bone maturation. BO: anorganic bovine bone mineral; HC: haversian canal; NB: new bone; CB: cortical bone. The healing time was 6 months (Figs 1-13 and 1-14). The implants were placed about a millimeter subcrestally. A tissue level implant placed into the bone with the polished collar 1 mm into the bone would be an excellent choice in the posterior region. The same patient had the other side grafted 10 months earlier. Due to scheduling issues, one side healed for longer than the other, but now the two phases of maturation can be compared. The ridge defects were similarly narrow (Figs 1-15 to 1-21). Fig 1-11 The outer surface of the ‘baby bone’ demonstrating irregularity and less maturity than the inner layer of the newly formed bone. This outer layer, referred to in this book as the ‘smear layer’ (see arrow), is about 1.5 mm in width. It will be remodeled and ‘shredded off’ during maturation. Fig 1-12 Image showing an area where corticalization has begun. Figs 1-13 and 1-14 Clinical example of a posterior mandibular ridge augmentation using the Sausage technique. Note that some of the area is corticalized, whereas other parts are still in maturation. Figs 1-15 and 1-16 Occlusal and labial views of a narrow posterior mandibular ridge. Fig 1-17 Labial view of the graft consisting of a 1:1 ratio of autogenous bone mixed with anorganic bovine bone mineral (ABBM). Figs 1-18 and 1-19 Labial and occlusal views of the fixated and stretched collagen membrane in place. In this book, the smear layer will be highlighted, especially in the anterior maxilla chapters where it will be modified and preserved using the Mini Sausage technique as a secondary bone graft protecting the newly formed ridge. The clinician should bear in mind that the smear layer will be either lost or modified. In most posterior cases, it is allowed to be shredded off, placing the implants deeper into the bone, whereas in the esthetic region, the Mini Sausage technique is used to prevent its resorption. These clinical procedures are exciting, and knowing the biology and dynamics of bone formation is essential to success. Fig 1-20 Occlusal view of the mature, corticalized, newly formed ridge. Fig 1-21 Note the excellent cortical bone formation. Dense versus perforated membrane The use of a membrane in GBR has been evaluated successfully for decades in multiple clinical and preclinical investigations. The role of the membrane has been determined to exclude competing cells such as fibroblasts. The clinical experience demonstrated that an important role of the membrane is to stabilize the bone graft. This has been well demonstrated in the Sausage technique using a collagen membrane and titanium pins for immobilization. In the author’s experience, the Sausage technique has resulted in the best bone quality and is usually faster and better than PTFE membranes. The native collagen membrane allows transvascularization and a possible accumulation of osseoinductive stimuli from the periosteum. In addition, the fast resorption of the collagen may also play a part in the maturation of the graft, since the periosteum holds vessels as well as mesenchymal cells that can turn into bone-forming cells. Therefore, a perforated membrane might help in bone formation. The goal is to develop ‘sausage-like’ bone quality faster. One idea was to perforate PTFE membranes to allow faster bone maturation. In several preclinical investigations, different aspects of this idea were investigated, as is shown in the following subsections. I. Dense vs perforated membrane using bone morphogenetic protein-2 (BMP-2) as a graft The osseoinductive action of BMP-2 depends on the presence of mesenchymal cells. The question is: How important are these types of cells in the periosteum versus the bone surface and the blood clot? Dense versus perforated membrane was compared in a chronic vertical defect (Figs 1-22 to 1-24). The results demonstrated significantly more bone fill when using the perforated membrane. The non-perforated membrane usually demonstrated appositional bone formation from the host bone with a lack of bone formation under the membrane (Figs 1-25 to 1-27). These results demonstrated that the communication with the periosteum might be important when a graft containing BMP-2 is being used, such as autogenous particles. II. Perforated vs non-perforated membranes using an osteoconductive graft material This experiment focused on the vascularization and bone formation activity of the newly formed bone. A xenogenic bone graft was used without any growth factors or autogenous bone. The perforated membrane was used with and without a...


Dr. Urban received his DMD degree and subsequently his MD degree from Semmelweis University School of Medicine and Dentistry (Budapest, Hungary) in 1991 and 1996. He completed a full time program in oral surgery at St. Istvan Hospital in Budapest, Hungary (1992-1996). He completed his internship program in Periodontics at UCLA. After he graduated from the Fellowship Program (1999-2000) in Implant Dentistry at Loma Linda University in Loma Linda, California, he was appointed assistant professor the following year. Dr. Urban teaches implant dentistry in the graduate program at Loma Linda University. He is licensed in the state of California (USA) and has a private practice in Budapest, Hungary. Dr. Urban received his PhD degree in Periodontlogy in 2012 at the University of Szeged, Hungary. He is currently an honorary professor at the University of Szeged. Dr. Urban is a board member of the Osteology Foundation and has published scientific articles and text book chapers on bone regeneration and soft tissue reconstructive surgery around dental implants.


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