Van Eeckhaut / Michotte Chiral Separations by Capillary Electrophoresis

Erscheinungsjahr 2009
ISBN: 978-1-4200-6934-1
Verlag: Taylor & Francis
Format: PDF
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)

E-Book, Englisch, 543 Seiten

Reihe: Chromatographic Science Series

Covers the Fundamentals of Chiral Separation, Available Chiral Selectors, and Numerous Applications of Chiral Separation by Capillary Electrophoresis
Since the 1980s, modern analytical tools have enabled capillary electrophoresis to become a standard part of the chemist’s toolkit. With contributions from international experts, Chiral Separations by Capillary Electrophoresis provides a general overview of the principles of chiral separation by capillary electrophoresis and the different chiral selectors available.

The book discusses the most important as well as several new chiral selectors used in capillary electrophoresis. It reviews recent pharmaceutical and biomedical applications and explores novel techniques, such as capillary electrophoresis coupled to mass spectrometry and microchip technology. The book also examines the quantitative aspects of capillary electrophoresis, the possibilities of capillary electrochromatography, and the various chiral columns available.

Capillary electrophoresis has proven to be an effective tool for chiral separation. This book explains how this technique can be used in the separation of molecules, offering insight into both existing and emerging applications.

Zielgruppe

Separation scientists, analytical chemists, pharmaceutical scientists, and graduate students in chemistry.

Autoren/Hrsg.

Van Eeckhaut, Ann

Michotte, Yvette

Fachgebiete

• Naturwissenschaften Chemie Analytische Chemie Instrumentelle Analytik, Chromatographie
• Technische Wissenschaften Verfahrenstechnik | Chemieingenieurwesen | Biotechnologie Biotechnologie

Inhaltsverzeichnis

Pharmacological Importance of Chiral Separations, Ann Van Eeckhaut and Yvette Michotte
Principles of Chiral Separations by Free-Solution Electrophoresis, Radim Vespalec
Cyclodextrin-Mediated Chiral Separations, Gerald Gübitz and Martin G. Schmid
Factors Influencing Cyclodextrin-Mediated Chiral Separations, Anne-Catherine Servais, Jacques Crommen, and Marianne Fillet
Macrocyclic Antibiotics as Chiral Selectors, Salvatore Fanali, Zeineb Aturki, Giovanni D’Orazio, and Anna Rocco
Chiral Separations Using Proteins and Peptides as Chiral Selectors, Jun Haginaka
Chiral Ligand Exchange Capillary Electrophoresis, Vincenzo Cucinotta and Alessandro Giuffrida
Chiral Separations by Micellar Electrokinetic Chromatography, Joykrishna Dey and Arjun Ghosh
Chiral Microemulsion Electrokinetic Chromatography, Kimberly A. Kahle and Joe P. Foley
Chiral Separations in Nonaqueous Media, Ylva Hedeland and Curt Pettersson
Quantitative Analysis in Pharmaceutical Analysis, Ulrike Holzgrabe, Claudia Borst, Christine Büttner, and Yaser Bitar
Analysis of Chiral Drugs in Body Fluids, Pierina Sueli Bonato, Valquira Aparcida Polisel Jabor, and Anderson Rodrigo Moraes de Oliveira
Chiral Capillary Electrophoresis-Mass Spectrometry, Serge Rudaz, Jean-Luc Veuthey, and Julie Schappler
Enantioseparations by Capillary Electrochromatography, Michael Lämmerhofer
Recent Applications in Capillary Electrochromatography, Debby Mangelings and Yvan Vander Heyden
Chiral Separations with Microchip Technology, Markéta Vlcková, Franka Kalman, and Maria A. Schwarz
Index

Über Autor(innen)

Ann Van Eeckhaut is a postdoctoral researcher in the Department of Pharmaceutical Chemistry and Drug Analysis in the School of Pharmacy at the Vrije Universiteit Brussel in Belgium.
Yvette Michotte is the head of the Department of Pharmaceutical Chemistry and Drug Analysis in the School of Pharmacy at the Vrije Universiteit Brussel in Belgium.