Wodarz Killer Cell Dynamics
1. Auflage 2007
ISBN: 978-0-387-68733-9
Verlag: Springer US
Format: PDF
Kopierschutz: 1 - PDF Watermark
Mathematical and Computational Approaches to Immunology
E-Book, Englisch, 220 Seiten, Web PDF
Reihe: Mathematics and Statistics (R0)
ISBN: 978-0-387-68733-9
Verlag: Springer US
Format: PDF
Kopierschutz: 1 - PDF Watermark
This book shows how mathematical and computational approaches can be useful to help us understand how killer T-cell responses work to fight viral infections. It also demonstrates that such mathematical and computational approaches are most valuable when coupled with experimental work through collaborations. The interdisciplinary spirit of the research and analysis is reflected in the writing style of the book. While the topic of the book is mathematical modeling, the text is written in such a way that experimental immunologists and virologists without extensive computational background will be able to understand the arguments, and to see the biological implications of theory. The book covers a broad variety of topics, including both basic immunological questions and the application of these insights to the understanding and treatment of pathogenic human diseases.
Zielgruppe
Research
Autoren/Hrsg.
Weitere Infos & Material
Viruses and Immune Responses: A Dynamical View.- Models of CTL Responses and Correlates of Virus Control.- CTL Memory.- CD4 T Cell Help.- Immunodominance.- Multiple Infections and CTL Dynamics.- Control versus CTL-Induced Pathology.- Lytic versus Nonlytic Activity.- Dynamical Interactions between CTL and Antibody Responses.- Effector Molecules and CTL Homeostasis.- Virus-Induced Subversion of CTL Responses.- Boosting Immunity against Immunosuppressive Infections.- Evolutionary Aspects of Immunity.
