Adinoff / Stein Neuroimaging in Addiction

1. Auflage 2011
ISBN: 978-1-119-97270-9
Verlag: John Wiley & Sons
Format: EPUB
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)

E-Book, Englisch, 352 Seiten, E-Book

Neuroimaging in Addiction presents an up-to-date,comprehensive review of the functional and structural imaging humanstudies that have greatly advanced our understanding of thiscomplex disorder. Approaching addiction from a conceptual ratherthan a substance-specific perspective, this book integrates broadneuropsychological constructs that consider addiction as aneuroplastic process with genetic, developmental, andsubstance-induced contributions.
The internationally recognized contributors to this volume areleaders in clinical imaging with expertise that spans the addictionspectrum.
Following a general introduction, an overview of neuralcircuitry and modern non-invasive imaging techniques provides theframework for subsequent chapters on reward salience, craving,stress, impulsivity and cognition. Additional topics include theuse of neuroimaging for the assessment of acute drug effects,drug-induced neurotoxicity, non-substance addictive behaviors, andthe application of imaging genetics to identify unique intermediatephenotypes. The book concludes with an exploration of the futurepromise for functional imaging as guide to the diagnosis andtreatment of addictive disorders.
Scientists and clinicians will find the material in this volumeinvaluable in their work towards understanding the addicted brain,with the overall goal of improved prevention and treatment outcomesfor patients.
Features a Foreword by Edythe London, Director of the Center forAddictive Behaviors, University of California at Los Angeles.

Autoren/Hrsg.

Adinoff, Bryon

Stein, Elliot A.

Über Autor(innen)

Dr. Adinoff is the Chief of the Division on Addictions inthe Department of Psychiatry at University of Texas SouthwesternMedical Center in Dallas and a staff psychiatrist at the VA NorthTexas Health Care System. He also holds the DistinguishedProfessorship of Alcohol and Drug Abuse Research at UTSouthwestern. Dr. Adinoff obtained his medical training at MichiganState University and completed his residency in psychiatry atTulane University. Following a fellowship and attending position inthe Laboratory of Clinical Studies at the National Institutes onAlcohol Abuse and Alcoholism, Dr. Adinoff joined the faculty of theMedical University of South Carolina as director of the substanceabuse program at the Ralph H. Johnson VA Medical Center. Dr.Adinoff's laboratory has used a variety of pharmacologic,cognitive, and behavioral probes to explore the neural andendocrine disruptions that occur following chronic cocaine oralcohol abuse and, more recently, compulsive tanning. Dr. Adinoffhas published over 100 articles, reviews, and book chapters on thebiology and treatment of addiction. He is also active inteaching trainees and colleagues how the brain disruptionsuncovered by neuroimaging research relate to relapse and recovery.
Dr. Elliot Stein is Chief of the Neuroimaging ResearchBranch at the National Institute on Drug Abuse Intramural ResearchProgram (NIDA-IRP). Prior to coming to NIDA in 2002, he wasProfessor of Psychiatry at the Medical College of Wisconsin (MCW),where he was also Professor in the Departments of Pharmacology,Neurobiology and the Biophysics Research Institute. He received hisPhD from the University of Maryland School of Medicine inneurophysiology and completed a post-doctoral fellowship at theCalifornia Institute of Technology with James Olds, a pioneer inbrain reward systems. His lab pioneered the development andapplication of fMRI to study the neurobiology of human drug abuse.His research program employs multiple MR imaging modalities(including MR spectroscopy, BOLD activation, functionalconnectivity and diffusion tensor imaging) to define those neuronalsystems mediating the actions of such abused drugs as nicotine andcocaine, to determine CNS sites and mechanisms responsible formediating drug craving and reinforcement, and how drugs interactwith specific cognitive and affective processes to alterbehavior.His research also incorporates preclinical models totranslationally link the more mechanistic preclinical work with themore observational human studies. He has more than 400 authoredpapers, abstracts, reviews and book chapters in the field of drugaddiction.