Ahmad / Basha Spectroscopic Data of Steroid Glycosides

Volume 6
1. Auflage 2010
ISBN: 978-0-387-39580-7
Verlag: Springer US
Format: PDF
Kopierschutz: 1 - PDF Watermark

E-Book, Englisch, 696 Seiten, eBook

Spectroscopic Data of Steroid Glycosides serves as an essential reference guide containing spectroscopic, physical and biological activity data of over 3500 steroid glycosides, offering the structures and the data of the naturally occurring glycosides of steroids. All compounds are arranged according to the structure of the aglycone, and, in its own class, according to the increasing molecular weight, making Spectroscopic Data of Steroid Glycosides extremely useful for the structure elucidation of new natural products, particularly glycosides.Spectroscopic Data of Steroid Glycosides offers a practical desk reference for all scientists and students interested in steroid glycosides and their biological and medicinal importance. The following data of the steroid glycosides, as available in published literature, are included: - Name of the compound, Chemical name of compound and its structure, - Source, name of the genus, species, authors, family of the biological source from which the glycoside has been isolated, - Melting point, - Specific rotation, - Molecule weight, - Molecular formula, - UV spectral data : maxima, e or log e , solvent, - IR peaks in cm -1 with medium in which the spectrum was taken e.g. KBr, nujol, etc, - Proton magnetic resonance (PMR) chemical shifts, multiplicity of the peaks, coupling constants with assignments, - 13 C-NMR (CMR) chemical shifts with assignments, - Mass spectral data with the technique used (e.g. Electron Impact (E.I.), Fast Atom Bombardment (FAB), positive ion or negative ion mode or any other technique, - CD or ORD data, - Biological Activity, - Full reference from which data have been taken.

Zielgruppe

Research

Autoren/Hrsg.

Ahmad, Viqar Uddin

Basha, Anwer

Inhaltsverzeichnis

Pregnane.- Gymnepregoside O.- Telosmoside A11.- Asclepias Fruticosa Saponin 12.- Asclepias Fruticosa Saponin 13.- Asclepias Incarnata Saponin 78.- Asclepias Incarnata Saponin 93.- Telosmoside A12.- Hoyacarnoside K.- Asclepias Incarnata Saponin 79.- Asclepias Fruticosa Saponin 16.- Hoyacarnoside T.- Asclepias Incarnata Saponin 92.- Cynafoside D.- Araujia Sericifera Glycoside 16.- Gymnepregoside L.- Leptadenia Hastata Saponin 25.- Causiaroside II.- Tacca Chantrieri Saponin 8.- Stephanoside P.- Gymnemaroside B.- Hainaneoside B.- Marstomentoside O.- Marstomentoside P.- Periplocoside F.- Auriculoside A.- Cynanchum Caudatum Saponin 61.- Cynanchum Caudatum Saponin 64.- Wilfoside C 1G.- Nigroside A.- Asclepias Fruticosa Saponin 14.- Asclepias Fruticosa Saponin 15.- Teikaside B-IVa.- Asclepias Incarnata Saponin 16.- Asclepias Incarnata Saponin 17.- Asclepias Fruticosa Saponin 17.- Asclepias Fruticosa Saponin 18.- Cynafoside C.- Leptadenia Hastata Saponin 30.- Araujia Sericifera Glycoside 20.- Leptadenia Hastata Saponin 14.- Hainaneoside A.- Dregeoside AO1.- Asclepias Incarnata Saponin 23.- Asclepias Incarnata Saponin 24.- Wallicoside.- Asclepias Fruticosa Saponin 19.- Asclepias Fruticosa Saponin 20.- Asclepias Fruticosa Saponin 21.- Asclepias Incarnata Saponin 90.- Cynauricuoside A.- Asclepias Incarnata Saponin 18.- Asclepias Incarnata Saponin 19.- Asclepias Tuberosa Saponin 10.- Telosmoside A5.- Araujia Sericifera Glycoside 21.- Metaplexis Japonica Saponin 24.- Hoyacarnoside M.- Asclepias Incarnata Saponin 25.- Leptadenia Hastata Saponin 15.- Leptadenia Hastata Saponin 32.- Leptadenia Hastata Saponin 10.- Leptadenia Hastata Saponin 27.- Alpinoside C.- Cynaphylloside H.- Telosmoside A3.- Cynafoside H.- Periplocoside E.- Teikaside C-IVa.- Hoyacarnoside O.- Gymnepregoside I.- Gymnepregoside J.- Alpinoside A.- Leptadenia Hastata Saponin 13.- Leptadenia Hastata Saponin 28.- Marstenacisside D.- Condurangoglycoside E3.- Condurangoglycoside A1.- Condurangoglycoside C1.- Anasteroside B.- Asclepias Tuberosa Saponin 8.- Cynanchum Caudatum Saponin 56.- Cynanchum Caudatum Saponin 57.- Cynanchum Caudatum Saponin 58.- Marstomentoside A.- Periplocoside K.- Asclepias Tuberosa Saponin 9.- Cynanchum Caudatum Saponin 62.- Wilfoside G 1G.- Cynanchum Caudatum Saponin 65.- Cynanchum Caudatum Saponin 67.- Cynanchum Caudatum Saponin 70.- Telosmoside A14.- Marstomentoside K.- Marstomentoside L.- Gymnepregoside B.- Gymnepregoside K.- Periplocoside D.- Leptadenia Hastata Saponin 11.- Leptadenia Hastata Saponin 17.- Leptadenia Hastata Saponin 29.- Cynanchum Caudatum Saponin 66.- Cynanchum Caudatum Saponin 68.- Cynanchum Caudatum Saponin 69.- Cynanchum Caudatum Saponin 71.- Sibiricoside E.- Asclepias Tuberosa Saponin 7.- Telosmoside A15.- Telosmoside A17.- Telosmoside A16.- Gymnepregoside E.- Metaplexis Japonica Saponin 25.- Metaplexis Japonica Saponin 26.- Marstomentoside Q.- Marstomentoside G.- Asclepias Tuberosa Saponin 11.- Telosmoside A18.- Asclepias Tuberosa Saponin 16.- Cestrum Nocturnum Saponin 8.- Periplocoside A.- Marstomentoside H.- Marstomentoside I.- Gymnepregoside P.- Leptadenia Hastata Saponin 33.- Gymnepregoside M.- Gymnepregoside N.- Gymnepregoside Q.- Cynanchum Caudatum Saponin 72.- Asclepias Tuberosa Saponin 12.- Cynauricuoside C.- Illustrol 3-O-?-D-Cymaropyranoside.- Hirundoside A.- Amaloside A.- Cynatratoside A.- Oleaside A.- Cynapanoside A.- Glaucoside A.- Paniculatumoside A.- Paniculatumoside B.- Tylophoriside A.- Oleaside B.- Cynaversicoside C.- Neocynaversicoside.- Atratoglaucoside A.- Amaloside B.- Oleaside C.- Komaroside A.- Oleaside D.-Atratoside D.- Cynascyroside A.- Cynascyroside D.- Cynatroside A.- Cynatroside C.- Atratoside A.- Cynatratoside B.- Cynatratoside C.- Cynatroside B.- Tylophoside A.- Stauntoside B.- Cynaforroside A.- Cynapanoside B.- Cynapanoside C.- Glaucoside C.- Glaucoside D.- Glaucoside G.- Cynanversicoside-A.- Cynatratoside F.- Glaucoside B.- Glaucoside E.- Glaucoside F.- Tylophoside B.- Tylophoside C.- Neocynapanoside A.- Tylophoside D.- Atratoglaucoside B.- Cynaversicoside D.- Komaroside C.- Oleaside E.- Komaroside B.- Oleaside F.- Cynascyroside C.- Cynascyroside E.- Cynascyroside B.- Atratoside C.- Atratoside B.- Cynatratoside D.- Cynatratoside E.- Stauntoside A.- Glaucoside H.- Cynanversicoside-B.- Glaucoside I.- Tylophoside E.- Glaucoside J.- Cynaversicoside E.- Tylophoroside.- Acetyltylophoroside.- Velutinoside A.- Androstane.- Ascandroside.- Androst-8-EN-Glycoside.- Vernonia Colorata Glycoside 2.- Latespinoside D.- Vernonia Colorata Glycoside 1.- Misc..- Carolinoside.

Leseproben

"PREFACE (p. vi-vii)

The present volumes reproduce the spectroscopic data of naturally occurring steroidal glycosides as far as they are available in the chemical literature published until the end of 2004. Steroids have the basic skeleton of cyclopentanoperhydrophenanthrene. Generally they do not have methyl groups attached to C-4 and thus differ from triterpenes. Many of the steroidal glycosides, or saponins, have interesting biological activities and constitute the active principles of the natural drugs.

The cardiac glycosides (cardenolides) included in the present work act as life-saving medicines in certain ailments. Not included in this work are the glycosides of steroidal alkaloids. However, the compounds which contain a nitrogen atom in the sugar or in the ester moiety (e.g. nicotinoyl moiety) are included. The steroidal glycosides are arranged according to the class of their aglycones (steroidal parts). Within each class increasing molecular weight is taken as the basis for this arrangement. If the compounds of the same class have the same molecular weight, then the glycosides with lesser number of carbon atoms come earlier than those with more carbon atoms. Finally, if all these factors are the same, then the compounds are arranged in alphabetical order.

The chemical shifts in the proton nuclear magnetic resonance (PMR) spectral data are arranged according to the increasing d (ppm) values. Each signal represents one proton unless indicated otherwise. The small alphabets used as superscript in PMR and 13C-NMR (CMR)-spectral data mean that the assignments are ambiguous and may be reversed with signals having the same superscripts. The signals masked by solvent peaks or by other signals of the compound are marked by an asterisk. Compounds can be easily located in this book with the help of the four indexes at the end of the last volume.

The trivial names of the compounds given by the original authors are used as the heading of the compound. If no trivial name has been given, then the name of the plant from which the glycoside has been isolated followed by the word “saponin” or “glycoside” and then the numerical order are used as the main heading. For the subheading, the name of the aglycone (trivial names if available) followed by names of the sugars are used with clear indication of glycosidic linkages and branching of the sugar chain if present.

I am very grateful to Ms. Judy Watson of Chemical Abstract Service who has helped me greatly in finding the registry numbers of several compounds. This work would not have been possible without the help of literature surveyors Dr. Akbar Ali, Dr. Hidayat M. Khan, Dr. M. Athar Abbasi, Mr. Touseef Ali Khan, Mr. Umair Quyyum Khan, Miss. Humera Zaheer, Miss. Rukhsana Kausor, Miss Husna Qamar, Miss. Fouzia Shamim, Ms. Zeenat Siddiqui, Muhammad Zubair, Afsar Khan, and Shazia Yasmeen to whom my sincere thanks are due. The whole book has been typed, composed, and structures drawn by Mr. Rafat Ali, Mr. Shabbir Ahmed, and Tariq Ilyas and I wish to express my sincere thanks to them."

Über Autor(innen)

Professor Viqar Uddin Ahmad has been associated with the HEJ Research Institute of Chemistry since its establishment in 1967. Prof. Viqar's currents interests are on isolation and structure elucidation of new natural products. Some of them have interesting biological activities. For example: VArious eudesmane sesquiterpenes which showed antibacterial activity against Escherichia coli, Klebsiella ozaenoe, K. pneumonieae, Proteus vulgaris, Shigella boddi, Staphylococcus aureus, S. pyogenes andB. anthracis; some triterpenoidal and steroidal saponins exhibited toxicity in Brine Shrimp Lethality bioassay and antibacterial activity against Pseudomonas pseudomaliae, Co-rynebactterium xerosis etc. One of the saponins isolated from a Trukish plant manifested hypotensive activity in anaesthetized rat.Prof. Viqar Uddin Ahmad availed a Fulbright Fellowship of nine months in 1993. during his stay at Cornell University, Itacha, USA. Prof. Viqar Uddin Ahmad worked on the twelve step total synthesis of and alkaloid isolated from an insect. Prof. Viqar also dilivered lecturers in the chemistry departments of Central Michighan University, Michighan, Georgia Tech, Atlanta, georgia, State University, Atlanta, Georgia and Cornell University, Ithaca.