Asherson / Cervera / Triplett Vascular Manifestations of Systemic Autoimmune Diseases

Erscheinungsjahr 2010
ISBN: 978-1-4200-4039-5
Verlag: Taylor & Francis
Format: PDF
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)

E-Book, Englisch, 624 Seiten

Not too long ago, it was thought that inflammation of blood vessels was the sole manifestation of systemic autoimmune diseases. Today, however, we know that disorders of coagulation, injuries to both neutrophils and endothelial cells, and certain lipids and amino acids are all intricately involved in the development of vascular disease. How are all these processes linked? What strategies can we employ or develop to halt the progression of vascular damage? What are the best ways to control acute vasculitis and vasospasm therapeutically? What are the risks and benefits of various strategies for the prevention of clotting? How soon should we initiate preventive strategies that protect blood vessels from arteriosclerosis in people with acute rheumatic diseases? What should be the nature of those strategies?

Vascular Manifestations of Systemic Autoimmune Diseases provides answers to all these questions. Ronald Asherson, Richard Cervera,Steven B. Abramson, Jean-Charles Piette, and Douglas Triplett- all international experts in the field-have assembled a collection of works that provide a comprehensive analysis of vascular irregularities. Now that most individuals survive the onset of acute systemic autoimmune diseases and live for decades more, halting the long-term attack on vasculature is increasingly important.
Vascular Manifestations of Systemic Autoimmune Diseases not only describes the clinical symptoms of vascular diseases; it also covers in one volume the many mechanisms involved in the pathogenesis of these disorders and addresses the newest treatments available for them.

Zielgruppe

Clinicians, internists, rheumatologists, hematologists, neurologists, surgeons, vascular surgeons, and clinical immunologists

Autoren/Hrsg.

Asherson, Ronald A.

Cervera, Ricard

Triplett, Douglas A.

Abramson, Steven B.

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Kardiologie, Angiologie, Phlebologie

Inhaltsverzeichnis

Section I: Mechanisms of Vascular Disease
Pathology of Vascular Disease, H. Terence Cook and Charles D. Pusey
Coagulation Abnormalities, Douglas A. Triplett
Antiphospholipid Antibodies, Robert A. S. Roubey
Platelet Disorders in Autoimmune Diseases
Ronit Simantov and Babette B. Weksler
Immunology of Atherosclerosis, Outi Vaarala
Homocysteine and Vascular Disease in the
Autoimmune Connective Tissue Diseases,
Michelle Petri
Vascular Tone Control and Raynaud´s Phenomenon,
Marco Matucci-Cerinic, Sergio Generini, Pan Sheng Fan,and M. Bashar Kahaleh
Antineutrophil Cytoplasmic Antibodies,
Xavier Bosch and Josep Font
Antiendothelial Cell Antibodies, Pier Luigi Moroni, Nicoletta del Papa, Elena Raschi
Cryoglobulins, Mario García-Carrasco, Manel Ramos-Casals, Ricard Cervera, and Josep Font
Markers of Endothelial Damage, David P. D'Cruz
Systemic Inflammatory Response Syndrome,
Systemic Lupus Erythematosus, and
Thrombosis, H. Michael Belmont and Steven B.
Abramson
Leukocyte Cell Adhesion Molecules in Vasculitis,
Jan Willem Cohen Tervaert, and Cees G. M. Kallenberg
Experimental Induction of Vascular Disease
Ilan Krause, Miri Blank, Yehuda Shoenfeld
Hormones and Vascular Disease, Joan T. Merrill and Robert G. Lahita
Section II: Clinical Manifestations
Vascular Manifestations in Necrotizing and
Granulomatous Vasculitides, Karim Raza, David
M. Carruthers, Paul A. Bacon
Vascular Manifestations in Giant-Cell Arteritis,
María C. Cid, José Hernández-Rodríguez, Josep M. Grau
Vascular Manifestations in Takayasu Arteritis, Fujio Numano
Vascular Manifestations in Systemic Lupus Erythematosus, Josep Font, Ricard Cervera, Miguel Ingelmo
Vascular Manifestations in the Antiphospholipid Syndrome, Ronald A. Asherson and Ricard Cervera
Vascular Manifestations in Sjögren´s Syndrome, Anne Parke
Vascular Manifestations of Progressive Systemic Sclerosis, Christopher P. Denton and Carol M. Black
Vascular Manifestations in Rheumatoid Arthritis,
Dermato/Polymyositis, and Mixed Connective
Tissue Disease, Jean-Charles Piette and Camille
Francès
Vascular Manifestations in Relapsing Polychondritis,
Jean-Charles Piette, Philippe Vinceneux, Camille Francès
Vascular Manifestations of Behçet´s Disease, Olcay Aydintug
Vascular Manifestations in Microangiopathic Syndromes, Gale A. McCarty
The Vasculitic Diseases of Childhood, Thomas J. A. Lehman
Pulmonary Hypertension, S.P. Wharton and T.W. Higenbottam
Renal Vasculitis, Michael Samarkos, Sozos Loizou, Kevin A. Davies
Skin Manifestations of Vasculitis,
Camille Francès, Pierre-André Bécherel, Jean-Charles Piette
Section III: Treatment
Pharmacological Treatments for Thrombotic Diseases,
Joan-Carles Reverter, Dolors Tàssies, Gerard Espinosa
Hormone Replacement Therapy for "At Risk"
Patients with Connective Tissue Diseases, Ann
Gompel
Surgical Treatments, Matthew Waltham and Kevin G. Burnand
Therapy of Systemic Vasculitis, David M. Carruthers, Karim Raza, Paul A. Bacon
Anticoagulation Therapy for the Antiphospholipid Syndrome, Scott Goodnight
The Treatment of Raynaud´s Phenomenon, Marco Martucci Cerinic, Sergio Generini, James R. Seibold
Treatment of Pulmonary Hypertension, S.P. Wharton and T.W. Higenbottam