Brown / Dickson Advances in Biomedical Engineering

Published Under the Auspices of the Biomedical Engineering Society
1. Auflage 2014
ISBN: 978-1-4832-1496-2
Verlag: Elsevier Science & Techn.
Format: PDF
Kopierschutz: 1 - PDF Watermark

E-Book, Englisch, 236 Seiten, Web PDF

Advances in Biomedical Engineering, Volume 5, is a collection of papers that deals with application of the principles and practices of engineering to basic and applied biomedical research, development, and the delivery of health care. The papers also describe breakthroughs in health improvements, as well as basic research that have been accomplished through clinical applications. One paper examines engineering principles and practices that can be applied in developing therapeutic systems by a controlled delivery system in drug dosage. Another paper examines the physiological and materials variables that can influence the stability of a biomaterial interface. The interface, in particular, concerns living and nonliving substances to create a functional and efficient replacement of a body part. For space use, NASA has developed bioinstrumentation systems that are reliable, safe, small, and subject-acceptable. Another paper examines the problems associated with the application of systems analysis to societies in the real world. The collection is suitable for biochemists, pharmacologists, bio-engineers, and investigators whose works involve biomedical engineering and drug therapeutics.

Autoren/Hrsg.

Brown, J. H. U.

Dickson, James F.

Inhaltsverzeichnis

1;Front Cover;1
2;Advances in Biomedical Engineering;4
3;Copyright Page;5
4;Table of Contents;6
5;Contributors;8
6;Preface;10
7;Contents of Previous Volumes;12
8;Chapter 1. Engineering Development of Therapeutic Systems: A New Class of Dosage Forms for the Controlled Delivery of Drugs;14
8.1;I. Introduction;15
8.2;II. Drug Therapy;15
8.3;III. Definition and Components of a Therapeutic System;18
8.4;IV. Portals Through Which Drugs May Be Deployed;23
8.5;V. Therapeutic Systems for Local Treatment;26
8.6;VI. Embodiments of Controlled, Constant Drug Delivery for Systemic Therapy;32
8.7;VII. Parameters in the Design of Therapeutic Systems;38
8.8;VIII. Testing Therapeutic Systems;43
8.9;IX. A Challenge to Pharmacologists;44
8.10;References;46
9;Chapter 2. Biomaterials—The Interfacial Problem;48
9.1;I. Introduction;49
9.2;II. Surface Chemistry of Materials;50
9.3;III. Wound Kinetics;72
9.4;IV. In Vitro Testing with Tissue Cultures;83
9.5;V. In Vivo Testing in Soft Tissues;89
9.6;VI. Soft Tissue Applications;100
9.7;VII. Transcutaneous Implants;106
9.8;VIII. Nonthrombogenic Surfaces;115
9.9;IX. Neural and Neuromuscular Implants;119
9.10;X. Orthopedic Implants;140
9.11;XI. General Theory;150
9.12;References;152
10;Chapter 3. Physiological Measurement Systems for Advanced Manned Space Missions;164
10.1;I. Introduction;164
10.2;II. Early Aerospace Physiological Measurement Systems;166
10.3;III. Extended-Duration Missions—Skylab;201
10.4;IV. Advanced Manned Space Missions;211
10.5;V. Conclusion;226
10.6;References;226
11;Chapter 4. Engineering Approaches to Societal Systems;230
11.1;I. Introduction;230
11.2;II. Health as a Major Parameter for the Performance of Social Systems;250
11.3;III. Methodology;267
11.4;IV. Applications;279
11.5;V. Conclusion;317
11.6;References;318
12;Subject Index;326