Carpi / Mechanick Thyroid Cancer

From Emergent Biotechnologies to Clinical Practice Guidelines
1. Auflage 2011
ISBN: 978-1-4398-6222-3
Verlag: Taylor & Francis
Format: PDF
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)

E-Book, Englisch, 408 Seiten

The current age of clinical medicine is witnessing biotechnological innovation at an unprecedented pace. As a result, the recently popularized clinical practice guidelines (CPG), as a tool to assist clinical decision-making, have been struggling to keep up. Thyroid Cancer: From Emergent Biotechnology to Clinical Practice Guidelines rides the wave of medical innovation, analyzing current and future CPG, and providing an up-to-date and comprehensive treatise on thyroid cancer, its diagnosis, and treatment.

A synthesis of ideas by prominent world experts in the field of thyroid cancer research and clinical practice, Thyroid Cancer covers:

- Technologically-advanced diagnostic procedures and therapeutic interventions

- Diagnostic techniques employed in the detection and follow-up of thyroid cancer including ultrasound, needle aspiration techniques, CT, PET, PET-CT, and MRI

- Basic principles of systems biology, molecular and translational medicine, CPG development, and risk stratification for thyroid cancer

- How CPG contain knowledge gaps and produce uncertainty

- Advances in the field, including new surgical techniques, molecular targeted therapies, external beam radiation therapy, and chemotherapy

A comprehensive, scientific description of current and future diagnostic and therapeutic modalities for the management of thyroid cancer, this treatise is an indispensible reference for both the specialist and referring physician.

Autoren/Hrsg.

Carpi, Angelo

Mechanick, Jeffrey I

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Onkologie, Krebsforschung
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Vorklinische Medizin: Grundlagenfächer Physiologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Endokrinologie

Inhaltsverzeichnis

Principles of Translational Medicine and Applications to Thyroid Cancer Investigation
Emily Jane Gallagher and Derek LeRoith

Systems Biology—An Overview
Ravi Iyengar and Azi Lipshtat

Genetic and Epigenetic Alterations in the MAP Kinase and PI3K/Akt Pathways in Thyroid Cancer
Mingzhao Xing and Paul W. Ladenson

Genetic and Molecular Pathophysiology of Medullary Thyroid Carcinoma
Rosa Maria Paragliola, Salvatore M. Corsello, Francesco Torino, and Agnese Barnabei

Risk Stratification in Differentiated Thyroid Cancer
Giuseppe Barbesino

Clinical Practice Guidelines for Thyroid Cancer: Where Are We Now?
Jeffrey I. Mechanick

Illustrative Case Studies of Thyroid Carcinoma and the Emerging Role of Molecular Medicine
Donald Bergman and Rhoda H. Cobin

Advances in Thyroid Ultrasound for Detection and Follow-Up of Thyroid Malignancies: Technical and Clinical Aspects
Laurence Leenhardt, François Tranquart, and Jean Tramalloni

Multimodality Imaging and Aspiration Biopsy Guidance in the Perioperative Management of Thyroid Carcinoma
Jing Gao, Jonathan K. Kazam, and Elias Kazam

The Use of Diagnostic Radiotracers in Thyroid Cancer
Josef Machac

PET-CT Scanning in the Management of Thyroid Cancer: Experience with a Cohort of 100 Patients
Dario Casara, Faise Al Bunni, Maria Rosa Pelizzo, and Fabio Pomerri

The Emerging Role of Percutaneous Needle Biopsy and Molecular Tumor Marker Analysis for the Preoperative Selection of Thyroid Nodules
Angelo Carpi, Jeffrey I. Mechanick, and Andrea Nicolini

Image-Guided Mini-Invasive Ablation of Thyroid Tumors and Distant Metastases
Enrico Papini, Antonio Bianchini, Rinaldo Guglielmi, Claudio M. Pacella,Irene Misischi, Laura Papini, and Giancarlo Bizzarri

Thyroidectomy and Neck Exploration: New Surgical Approaches
Jean-Christophe Lifante and William B. Inabnet III

Thyroid Surgery Performed under Local Anesthesia and Same-Day Surgery
Joseph DiNorcia and John D. Allendorf

The Use of Therapeutic Radiotracers in Thyroid Cancer
Josef Machac

External Beam Radiation Therapy in Thyroid Cancer
Walter Choi and Louis Harrison

Role of Chemotherapy in Thyroid Cancer
Paolo Bossi and Laura D. Locati

Role of NF- B in Thyroid Cancer
Eriko Suzuki, Shunichi Yamashita, and Kazuo Umezawa

Biologically Targeted Therapies for Thyroid Cancers
Steven I. Sherman

Molecular Targeted Therapies of Medullary Thyroid Carcinoma
Francesco Torino, Agnese Barnabei, Rosa Maria Paragliola, and Salvatore M. Corsello

Synthesis of Emergent Biotechnologies into Future CPG
Jeffrey I. Mechanick, Angelo Carpi, Mark Urken, Donald Bergman, and Rhoda H. Cobin

Über Autor(innen)

Angelo Carpi, MD is a clinical researcher at the University Hospital of Pisa. He is also an associate professor of Internal Medicine at Pisa University.
Jeffrey I. Mechanick, MD, Mount Sinai School of Medicine, New York City, is a Clinical Professor within the Department of Medicine, Division of Endocrinology, Diabetes, and Bone Disease at the Mount Sinai School of Medicine.