Kollerr / Allfrey / Allg”wer The Role of Chromosomes in Cancer Biology

Recent Results in Cancer Research
1. Auflage 2017
ISBN: 978-1-4831-9291-8
Verlag: Elsevier Science & Techn.
Format: PDF
Kopierschutz: 1 - PDF Watermark

E-Book, Englisch, 136 Seiten, Web PDF

The Role of Chromosomes in Cancer Biology provides a description of the molecular organization and function of chromosomes and the consequences of chromosomal aberrations in human development. The book presents accounts on the structure and function of the chromosome; the cellular features of primary tumors and ascetic fluid; the cytological actions of radiation and drugs and their relevance to therapy. Developmental disorders caused by chromosomal anomalies; chromosome aneuploidy in human malignancies; and viral oncogenesis are discussed as well. The book will prove to be very insightful to those involved in cancer research, oncologists, cytologists, and molecular biologists.

Autoren/Hrsg.

Kollerr, Peo C.

Allfrey, V. G.

Allgöwer, M.

Bauer, K. H.

Inhaltsverzeichnis

1;Fornt Cover;1
2;The Role of Chromosomes in Cancer Biology
;4
3;Copyright Page;5
4;Tabel of Contents;12
5;Foreword;8
6;Preface;10
7;Chapter 1. Chromosome Structure and Function;14
7.1;Summary;19
8;Chapter 2. Chromosomal Anomalies as the Causeof Developmental Disorders;20
8.1;1. Numerical Changes;21
8.2;2. Structural Changes;22
8.3;3. Chromosome Anomalies in the Foetus;23
8.4;4. Chromosomal Mosaicism;24
8.5;Summary;25
9;Chapter 3. Mitotic Anomalies in Tumours and Boveri's Theory;27
9.1;Summary;34
10;Chapter 4. Malignant Cell Populations and the Stemline Concept;35
10.1;Summary;42
11;Chapter 5. Chromosomal and Functional Differences in Malignant Cell Populations;43
11.1;Summary;50
12;Chapter 6. Primary Tumours in Animals;51
12.1;1."Spontaneous" Primary Tumours;51
12.2;2. Induced Primary Tumours;52
12.3;Summary;61
13;Chapter 7. Chromosome Aneuploidy in Human Malignancies: Effusions;62
13.1;Summary;71
14;Chapter 8. Chromosome Aneuploidy in Human Malignancies: Solid Tumours;72
14.1;Summary;76
15;Chapter 9. Marker Chromosomes and the Clonal Evolution of Chromosome Aberrations;78
15.1;Summary;83
16;Chapter 10. Chromosomes in Precancerous Lesions and in Tumour Development;84
16.1;Summary;92
17;Chapter 11. Chromosomal Predisposition to Cancer;93
17.1;Summary;100
18;Chapter 12. Chromosomes and Viral Oncogenesis;102
18.1;Summary;109
19;Chapter 13. Chromosomes and the Treatment of Cancer;110
19.1;Summary;121
20;Conclusion;122
21;References;124
22;Subject Index;133
23;Monographs already Published;136