Liang / Fang | Medicinal Chemistry of Bioactive Natural Products | E-Book | www.sack.de
E-Book

E-Book, Englisch, 336 Seiten, E-Book

Liang / Fang Medicinal Chemistry of Bioactive Natural Products


1. Auflage 2006
ISBN: 978-0-471-73933-3
Verlag: John Wiley & Sons
Format: PDF
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)

E-Book, Englisch, 336 Seiten, E-Book

ISBN: 978-0-471-73933-3
Verlag: John Wiley & Sons
Format: PDF
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)



Current discoveries and research into bioactive naturalproducts
Medicinal Chemistry of Bioactive Natural Products provides amuch-needed survey of bioactive natural products and theirapplications in medicinal chemistry. This comprehensive referencefeatures articles by some of the world's leading scientists in thefield on discovery, structure elucidation, and elegant syntheticstrategies--developed for natural products--with an emphasis on thestructure activity relationship of bioactive natural products. Thetopics have been carefully chosen on the basis of relevance tocurrent research and to importance as clinicially usefulagents.
Rather than attempting to be a comprehensive encyclopedia ofbioactive natural products, Medicinal Chemistry of BioactiveNatural Products guides the reader to the key developments in thefield. By providing not only practical detail but a historicalperspective on the chemistry and biology of the compounds underconsideration, the book serves as a handy resource for researchersin their own work developing pharmaceuticals, and as an inspiringintroduction for young scientists to the dynamic field of bioactivenatural products research.
Enhanced by examples with updated research results, the discussioncovers such topics as:
* The chemistry and biology of epothilones
* Vancomycin and other glycopeptide antibiotic derivates
* Antitumor and other related activities of Taxol and itsanalogs
* The antimalarial properties of the traditional Chinese medicine,Quinghaosu (artemisinin)
* Huperzine A: A natural drug for the treatment of Alzheimer'sdisease
* The medicinal chemistry of ginkgolides from Ginkgo biloba
* Recent progress in Calophyllum coumarins as potent anti-HIVagents
* Plant-derived anti-HIV agents and analogs
* Chemical synthesis of annonaceous acetogenins and theirstructurally modified mimics

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XIAO-TIAN LIANG received his BS degree from the NationalCentral University (China) in 1946 and his PhD degree from theUniversity of Washington at Seattle (USA) in 1951. Afterpostdoctoral work at Harvard University, he joined the faculty ofthe Institute of Materia Medica, Chinese Academy of MedicalSciences. In 1980, he was elected as an Academician of AcademiaSinica (Chinese Academy of Sciences) and has served on the advisoryeditorial boards of Tetrahedron and Tetrahedron Letters, amongother scientific journals. He coauthored more than 300 scientificpapers and reviews, and has written or edited more than ten books.
WEI-SHUO FANG graduated from Beijing Medical University,and obtained his PhD degree from Peking Union Medical College(PUMC) in 1997. After postdoctoral training in the US, he joinedthe faculty of the Institute of Materia Medica, Chinese Academy ofMedical Sciences & PUMC. He has conducted visiting study in theUniversity of Illinois at Urbana-Champaign and coauthored more thanthirty articles in peer-reviewed journals.



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