Lin / Li / Chan Principles and Applications of Asymmetric Synthesis

1. Auflage 2003
ISBN: 978-0-471-46524-9
Verlag: John Wiley & Sons
Format: PDF
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)

E-Book, Englisch, 536 Seiten, E-Book

Asymmetric synthesis remains a challenge to practicing scientistsas the need for enantiomerically pure or enriched compoundscontinues to increase. Over the last decade, a large amount ofliterature has been published in this field. Principles andApplications of Asymmetric Synthesis consolidates and evaluates themost useful methodologies into a one-volume resource for theconvenience of practicing scientists and students.
Authored by internationally renowned scientists in the field, thisreliable reference covers more than 450 reactions and includesimportant stoichiometric as well as catalytic asymmetric reactions.The first chapter reviews the basic principles, commonnomenclature, and analytical methods, and the remainder of the bookis organized according to reaction type. The text examines suchtopics as:
* Carbon-carbon bond formations involving carbonyls, enamines,imines, and enolates
* Asymmetric C-O bond formations including epoxidation,dihydroxylation, and aminohydroxylation
* Asymmetric synthesis using the Diels-Alder reaction and othercyclizations
* Applications to the total synthesis of natural products
* Use of enzymes in asymmetric synthesis
Practicing chemists in the pharmaceutical, fine chemical, andagricultural professions as well as graduate students will findthat Principles and Applications of Asymmetric Synthesis affordscomprehensive and current coverage.

Autoren/Hrsg.

Lin, Guo-Qiang

Li, Yue-Ming

Chan, Albert S. C.

Inhaltsverzeichnis

Preface.
Abbreviations.
Introduction.
-Alkylation and Catalytic Alkylation of Carbonyl Compounds.
Aldol and Related Reactions.
Asymmetric Oxidations.
Asymmetric Diels-Alder and Other Cyclization Reactions.
Asymmetric Catalytic Hydrogenation and Other ReductionReactions.
Applications of Asymmetric Reactions in the Synthesis of NaturalProducts.
Enzymatic Reactions and Miscellaneous Asymmetic Syntheses.
Index.

Über Autor(innen)

GUO-QIANG LIN, YUE-MING LI, and ALBERT S. C. CHAN are all professors in the Department of Chemical Technology at The Hong Kong Polytechnic University, Hong Kong, China.