Machin / Day / Green Textbook of Clinical Trials

2. Auflage 2007
ISBN: 978-0-470-01015-0
Verlag: John Wiley & Sons
Format: PDF
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)

E-Book, Englisch, 784 Seiten, E-Book

Now published in its Second Edition, the Textbook of ClinicalTrials offers detailed coverage of trial methodology indiverse areas of medicine in a single comprehensive volume.
Praise for the First Edition:
"... very useful as an introduction to clinical research, orfor those planning specific studies within therapeutic or diseaseareas." BRITISH JOURNAL OF SURGERY, Vol. 92, No. 2,February 2005
The book's main concept is to describe the impact ofclinical trials on the practice of medicine. It separates theinformation by therapeutic area because the impact of clinicaltrials, the problems encountered, and the numbers of trials inexistence vary tremendously from specialty to specialty. Thesections provide a background to the disease area and generalclinical trial methodology before concentrating on particularproblems experienced in that area. Specific examples are usedthroughout to address these issues.
The Textbook of Clinical Trials, SecondEdition:
* Highlights the various ways clinical trials have influenced thepractice of medicine in many therapeutic areas
* Describes the challenges posed by those conducting clinicaltrials over a range of medical specialities and allied fields
* Additional therapeutic areas are included in this SecondEdition to fill gaps in the First Edition as the numberand complexity of trials increases in this rapidly developingarea
* Newly covered or updated in the Second Edition: generalsurgery, plastic surgery, aesthetic surgery, palliative care,primary care, anaesthesia and pain, transfusion, wound healing,maternal and perinatal health, early termination, organtransplants, ophthalmology, epilepsy, infectious disease,neuro-oncology, adrenal, thyroid and urological cancers, as well asa chapter on the Cochrane network
An invaluable resource for pharmaceutical companies, theTextbook of Clinical Trials, Second Edition appealsto those working in contract research organizations, medicaldepartments and in the area of public health and health sciencealike.

Autoren/Hrsg.

Machin, David

Day, Simon

Green, Sylvan

Inhaltsverzeichnis

List of Contributors.
Preface to Second Edition.
Preface the First Edition.
INTRODUCTION.
1 The Development of Clinical Trials (SimonDay).
2 General Statistical Issues (David Machin).
3 The Cochrane Collaboration (Mike Clarke).
CANCER.
4 Breast Cancer (Donald A. Berry, Terry L. Smith andAman U. Buzdar).
5 Childhood Cancer (Sharon B Murphy and JonathanJ.Shuster).
6 Gastrointestinal Cancers (Daniel Sargent, RichardGoldberg and Paul Limburg).
7 Melanoma (Ping-Yu Liu and Vernon K. Sondak).
8 Respiratory Cancers (Joan H. Schiller and KyungmannKim).
9 Adrenal Cortical Carcinoma (Isha Malik and PetrosPerros).
10 Thyroid Cancer (Vijayaraman Arutchelvam and PetrosPerros).
11 Urologic Cancers (Edith D. Canby-Hagino, CatherineM. Tangen, and Ian M. Thompson).
12 Haematologic Cancers: Challenges in Developing NewTherapeutic Approaches (Charles A. Schiffer and Stephen L.George).
CARDIOLOGY.
13 Acute Stroke (Philip Bath).
14 Cardiovascular Disease (Krishna Prasad).
DENTISTRY AND ORAL HEALTH CARE.
15 Dentistry and Oral Health Care (May C.M. Wong,Colman McGrath and Edward C.M. Lo).
DERMATOLOGY.
16 Dermatology (Luigi Naldi and CosettaMinelli).
INFECTIOUS DISEASES.
17 HIV Infection (Michael D. Hughes).
18 Infectious Diseases (Ingela Krantz).
OPHTHALMOLOGY.
19 Ophthalmology (Jonathan C.K. Clarke and Peng-TeeKhaw).
PSYCHIATRY.
20 Anxiety Disorders (M. Katherine Shear and Philip W.Lavori).
21 Cognitive Behaviour Therapy (Nicholas Tarrier andTil Wykes).
22 Psychotherapy for Depression (Graham Dunn).
REPRODUCTIVE HEALTH.
23 Contraception (Gilda Piaggio and Timothy M.M.Farley).
24 Gynaecology and Infertility (Siladitya Bhattacharyaand Jill Mollison).
25 Early Pregnancy Termination (Beverly Winikoff andBatya Elul).
26 Maternal and Perinatal Health (Jos´e Villar,Allan Donner, Edgardo Abalos and Liana Camp´odonico).
RESPIRATORY.
27 Respiratory Medicine (AndersKällén).
SURGERY & ANAESTHESIA.
28 Anaesthesia and Pain (Paul S. Myles and JohnRigg).
29 General Surgery (Dr Olga Jonasson and DomenicReda).
30 Plastic Surgery - Reconstructive Surgery(Erik Ang and Woffles Wu).
31 Plastic Surgery - Aesthetic Surgery (WofflesWu and Erik Ang).
TRANSPLANTATION.
32 Renal Transplantation (VathsalaAnantharaman).
OTHER PROCEDURES.
33 Wound Healing (Colin Song and Edwin Chan).
34 Palliative Care (Robert S. Krouse and DavidCasarett).
35 Complementary Medicine (Ping-Chung Leung).
36 Cluster Randomized Trials in Health Care Research(Randall D. Cebul, Neal V. Dawson and Thomas E. Love).
37 Nursing (Nicola Crichton).
SPECIAL POPULATIONS.
38 Clinical Trials in Paediatrics (Johan P.E.Karlberg).
39 Clinical Trials Involving Older People (CarolJagger and Antony J. Arthur).
40 Clinical Trials in Rare Diseases (SimonDay).
Index.

Über Autor(innen)

David Machin, Division of Clinical Trials andEpidemiological Sciences, National Cancer Centre, Singapore.
Simon Day, Medicines and Healthcare Products RegulatoryAgency, London, UK.
Sylvan Green, Arizona Cancer Center, Tucson, Arizona,USA.