Morré ECTO-NOX Proteins

Growth, Cancer, and Aging
2013
ISBN: 978-1-4614-3958-5
Verlag: Springer US
Format: PDF
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)

E-Book, Englisch, 508 Seiten, eBook

This volume documents this unique family of cell surface proteins. Despite masquerading as intractable and difficult to clone and characterize, ENOX proteins have and continue to offer remarkable opportunities for research, commercial development and outside confirmation of therapeutic, diagnostic and new paradigms to help explain complex biological processes.

Zielgruppe

Research

Autoren/Hrsg.

Morré, D. James

Morré, Dorothy M.

Inhaltsverzeichnis

Preface.   Brief history of discovery and acknowledgments 1  The ECTO-NOX protein family2  Measurement of ECTO-NOX (ENOX) activities3  The constitutive ENOX1 (CNOX)4  Role in plasma membrane electron transport5  Role in the enlargement phase of cell growth6  Role as ultradian oscillators of the cells’ biological clock7  Other potential functional roles of ENOX proteins8  ENOX2 (tNOX) and cancer9  Age-related ENOX proteins (arNOX)10  The auxin-stimulated ENOX and auxin-stimulation of plant growth11  Cancer therapeutic applications of ENOX2 proteins12  Diagnostic applicastions of –ENOX2 proteinsAppendix A Epilogue: Remaining challengesAppendix B Detailed description of 2-D gel electrophoresis western blot early detection protocol