Niemeyer / Mirkin Nanobiotechnology

Concepts, Applications and Perspectives
1. Auflage 2006
ISBN: 978-3-527-60591-0
Verlag: Wiley-VCH
Format: PDF
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)

E-Book, Englisch, 469 Seiten, E-Book

Ein breit angelegter Überblick über das Forschungsgebiet der Nanobiotechnologie mit Beiträgen aus der bioorganischen und bioanorganischen Chemie, der Molekularbiologie, Bioanalytik und Materialwissenschaft. In den vier Hauptteilen werden Systeme mit Phasengrenzflächen, Nanostrukturen auf DNA-Basis, Nanostrukturen auf Proteinbasis sowie Verfahren zur Nanoanalytik besprochen. Jedes Kapitel wird ergänzt durch zahlreiche Verweise auf die Originalliteratur.

Autoren/Hrsg.

Niemeyer, Christof M.

Mirkin, Chad A.

Inhaltsverzeichnis

I INTERPHASE SYSTEMS
Biocompatible inorganic devices
Microfluidic "Lab-on-a-chip" devices
Microcontact printing of proteins
Cell-nanostructure interactions
Networks of neuronal cells on silicon substrates
II PROTEIN-BASED NANOSTRUCTURES
S-Layers
Engineered nanopores
Genetic appoaches to particle assembly
Microbial nanoparticle production
Magnetosomes
Bacteriorhodopsin technology
Polymer nanocontainers
Protein biomolecular motors
Nanoparticle-biomaterial hybrid systems
III DNA-BASED NANOSTRUCTURES
DNA-protein nanostructures
DNA-templated electronics
DNA-based metallic nanowires
Mineralization in nanostructured biocompartments
DNA-gold-nanoparticle conjugates
DNA nanostructures for mechanics and computing
Nanoparticles as non-viral transfection agents
IV NANOANALYTICS
Quantum dot biolabeling
Nanoparticle molecular labels
Analysis of biomolecular structure by AFM and molecular pulling
Force spectroscopy
Biofunctionalized nanoparticles for SERS and SPR
Bioconjucated silica particles in bioanalysis

I INTERPHASE SYSTEMS
Biocompatible inorganic devices
Microfluidic "Lab-on-a-chip" devices
Microcontact printing of proteins
Cell-nanostructure interactions
Networks of neuronal cells on silicon substrates
II PROTEIN-BASED NANOSTRUCTURES
S-Layers
Engineered nanopores
Genetic appoaches to particle assembly
Microbial nanoparticle production
Magnetosomes
Bacteriorhodopsin technology
Polymer nanocontainers
Protein biomolecular motors
Nanoparticle-biomaterial hybrid systems
III DNA-BASED NANOSTRUCTURES
DNA-protein nanostructures
DNA-templated electronics
DNA-based metallic nanowires
Mineralization in nanostructured biocompartments
DNA-gold-nanoparticle conjugates
DNA nanostructures for mechanics and computing
Nanoparticles as non-viral transfection agents
IV NANOANALYTICS
Quantum dot biolabeling
Nanoparticle molecular labels
Analysis of biomolecular structure by AFM and molecular pulling
Force spectroscopy
Biofunctionalized nanoparticles for SERS and SPR
Bioconjucated silica particles in bioanalysis

Über Autor(innen)

Christof M. Niemeyer is Professor of Chemistry at the University of Dortmund (Germany) where he holds the chair of Biological and Chemical Microstructuring. He was born in Cloppenburg and studied chemistry at the University of Marburg. He did his thesis at the Max-Planck-Institut für Kohlenforschung in Mülheim/Ruhr under the supervision of Manfred T. Reetz and his postdoctorate with Charles R. Cantor at the Center for Advanced Biotechnology in Boston (USA). He then went back to Germany, where he worked with Dietmar Blohm at the University of Bremen to complete his habilitation before moving to Dortmund as a full Professor in 2002. He is interested in semisynthetic DNA-protein and -nanoparticle conjugates and their applications in life-sciences, catalysis and molecular nanotechnology.
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Chad A. Mirkin is the George B. Rathmann Professor of Chemistry and the Director of the Institute for Nanotechnology and the Center for Nanofabrication and Molecular Self-Assembly at Northwestern University in Evanston.
Professor Mirkin holds a B.S. degree from Dickinson College (1986) and a Ph.D. degree in chemistry from The Pennsylvania State University (1989). He was a NSF Postdoctoral Fellow at the Massachusetts Institute of Technology before becoming a chemistry professor at Northwestern University in 1991.
Professor Mirkin is known for his development of nanoparticle-based biodetection schemes and his invention of Dip-Pen Nanolithography. He is the founder of two companies, Nanosphere and NanoInk, which are commercializing nanotechnology applications in the life science and semiconductor industries.
Professor Mirkin has been recognized for his accomplishments with the 2004 Nobel Laureate Signature Award for Graduate Education in Chemistry (2003), the 2003 Raymond and Beverly Sackler Prize in the Physical Sciences, the 2002 Feynman Prize in Nanotechnology, the 2001 Leo Hendrick Baekeland Award, the Discover 2000 Award for Technological Innovation, I-Street Magazine's Top 5 List for Leading Academics in Technology, the Materials Research Society Young Investigator Award (2000), the ACS Award in Pure Chemistry (1999), the PLU Fresenius Award (1998), the Harvard University E. Bright Wilson Prize (1998), and the BF Goodrich Collegiate Inventors Award (1997).