Scher / Kaye / Liu Essentials of Blood Product Management in Anesthesia Practice

1. Auflage 2021
ISBN: 978-3-030-59295-0
Verlag: Springer International Publishing
Format: PDF
Kopierschutz: Wasserzeichen (»Systemvoraussetzungen)

E-Book, Englisch, 478 Seiten, eBook

This comprehensive book is written to inform and improve outcomes of patients in need of blood management during surgical procedures. Information is presented in an accessible format, allowing for immediate use in clinical practice.
Beginning with an overview of the history of blood transfusions, early chapters present the foundational information needed to comprehend information in later chapters. Nuanced procedures, drugs, and techniques are covered, including new biologicals to assist clotting and blood substitutes. Further discussions focus on potential complications seen in blood transfusions, such as diseases of the coagulation system, pathogen transmissions, and acute lung injuries. Chapters also examine the complexities of treating specific demographics, of which include the geriatric patient and patients suffering from substance abuse. 
Essentials of Blood Product Management in Anesthesia Practice
 is an invaluable guide for anesthesiologists, surgeons, trauma physicians, and solid organ transplant providers.

Zielgruppe

Professional/practitioner

Autoren/Hrsg.

Scher, Corey S.

Kaye, Alan David

Liu, Henry

Perelman, Seth

Leavitt, Sarah

Inhaltsverzeichnis

The History of Blood TransfusionsModern Blood BankingComponent Therapy and Whole Blood: Packed Red Blood Cells, Fresh Frozen Plasma, Cryoprecipitate, washed and or radiated red cellsThe Coagulation System and Clot StabilityFibrinolysis- Tranexamic Acid and Aminocaproic Acid.Hypercoagulation and Thrombotic Disorders: TTP, Factor 5 Leiden, Phospholipid Syndrome, Anti-thrombin 3, hypereosinophils, oxidative stress, cancer.Diseases or Conditions of Platelet DysfunctionThe Massive Transfusion Protocol
New Biologicals to Assist Clotting- Riastap, Prothrombin Concentrates. Antithrombin3, Fibrogammin and factor13, Fibrosupernatant, Fibrinogen Concentrates, Recombinant Factor 7, DDAVP, Octaplast G., Factor 10A, KCentra
Biologicals that Inhibit Clot generation -The Heparins, Factor 10A inhibitors, rivaroxaban, apixaban, dabigatran,Point of Care Testing and Goal Directed Therapy- Thromboelastography, ROTEM, Platelet function analyzer, stat-PT, thrombin generation assays, multi-electro-aggregometry, OHP (Overall hemostatic potential assay), ACT.Complications of Blood Transfusions: TRALI, TACO, Blood type mismatch, infectionDiseases of the Coagulation System- Hemophilia, VonWillebrand Disease, Cryoglobulinemia, Inborn Errors of Factor SynthesisBlood Conservation Strategies and Bloodless Surgery- normovolemic hemodilution, cell saver,
Bridges to Transfusion when blood is not immediately available.
Artificial BloodPreoperative correction of anemiaBlood Deployment in Natural Disasters and the Military in CombatCommonly prescribed medications that affect clotting-anti-depressants, NSAIDS, ASAAnesthesia for the severe trauma patient- new evidence from new trialsOld blood vs. new blood- Is storage injury a concern?Vascular Endothelial dysfunction and inflammatory statesLiberal or restrictive blood transfusions

Über Autor(innen)

Corey Scher MDClinical Professor of AnesthesiologyNew York University School of MedicineBellevue Hospital Center New York, NY 

 Alan David Kaye MD, PhD Vice-Chancellor of Academic Affairs, Chief Officer, and Provost Tenured Professor, Departments of Anesthesiology and Pharmacology, Toxicology, and NeurosciencesLSU School of MedicineShreveport, LAUSA   Henry Liu MDProfessor of Anesthesiology & Perioperative MedicineMilton S. Hershey Medical CenterPenn State University College of MedicineHershey, PA USA Seth Perleman MDAssociate Professor of AnesthesiologyNew York University School of MedicineLangone Medical CenterNew York University School of Medicine

New York, NYUSASarah Leavitt MDAssistant ProfessorDepartment of AnesthesiologyNYU Langone Medical CenterBellevue HospitalNew York, NYUSA