Strauss Viruses and Human Disease

2. Auflage 2007
ISBN: 978-0-08-055316-0
Verlag: Elsevier Science & Techn.
Format: EPUB
Kopierschutz: 6 - ePub Watermark

E-Book, Englisch, 480 Seiten

Completely revised and updated, the new edition of this groundbreaking text integrates basic virology with pathophysiological conditions to examine the connection between virology and human disease. Most virology textbooks focus on the molecular biology involved without adequate reference to physiology. This text focuses on viruses that infect humans, domestic animals and vertebrates and is based on extensive course notes from James Strauss' virology class at the California Institute of Technology taught for over 30 years. Expertly depicting in color the molecular structure and replication of each virus, it provides an excellent overview for students and professionals interested in viruses as agents of human disease.
* Includes over 30% new material - virtually all of the figures and tables have been redrawn to include the latest information and the text has been extensively rewritten to include the most up-to-date information
* Includes a new chapter on emerging and reemerging viral diseases such as avian flu, SARS, the spread of West Nile virus across America, and the continuing spread of Nipah virus in Southeast Asia.
* Further reading sections at the end of each chapter make it easy find key references
* World maps depicting the current distribution of existing and newly emerging viruses are also incorporated into the text
* A companion website features illustrations for use in class notes and presentations.

Autoren/Hrsg.

Strauss, Ellen G.

Strauss, James H.

Inhaltsverzeichnis

1;Front Cover;1
2;Viruses and Human Disease;4
3;Copyright Page;5
4;Table of Contents;6
5;Preface to the Second Edition;8
6;Chapter 1: Overview of Viruses and Virus Infection;9
6.1;Introduction;9
6.2;Classification of Viruses;14
6.3;An Overview of the Replication Cycle of Viruses;15
6.4;Effects of Virus Infection on the Host Cell;37
6.5;Epidemiology: The Spread of Viruses from Person to Person;39
6.6;Further Reading;40
7;Chapter 2: The Structure of Viruses;43
7.1;Introduction;43
7.2;Helical Symmetry;43
7.3;Icosahedral Symmetry;44
7.4;Nonenveloped Viruses with More Complicated Structural Features;53
7.5;Enveloped Viruses;53
7.6;Assembly of Virions;66
7.7;Stability of Virions;69
7.8;Further Reading;70
8;Chapter 3: Plus-Strand RNA Viruses;71
8.1;Introduction;71
8.2;Family Picornaviridae;71
8.3;Family Caliciviridae;91
8.4;Family Hepeviridae;94
8.5;Family Astroviridae;95
8.6;Family Togaviridae;97
8.7;Family Flaviviridae;114
8.8;Family Coronaviridae;132
8.9;Family Arteriviridae;136
8.10;Family Roniviridae;138
8.11;The Plus-Strand RNA Viruses of Plants;138
8.12;Origin and Evolution of Plus-Strand RNA Viruses;140
8.13;Further Reading;142
9;Chapter 4: Minus-Strand RNA Viruses;145
9.1;Introduction;145
9.2;Overview of the Minus-Strand RNA Viruses;145
9.3;Family Rhabdoviridae;149
9.4;Family Paramyxoviridae;155
9.5;Family Filoviridae;166
9.6;Family Bornaviridae;169
9.7;Family Orthomyxoviridae;170
9.8;Family Bunyaviridae;183
9.9;Family Arenaviridae;191
9.10;Evolution of Minus-Strand RNA Viruses;196
9.11;Further Reading;197
10;Chapter 5: Viruses That Contain Double-Stranded RNA: Family Reoviridae;201
10.1;Introduction;201
10.2;Overview of the Family Reoviridae;201
10.3;Further Reading;217
11;Chapter 6: Viruses Whose Life Cycle Uses Reverse Transcriptase;219
11.1;Introduction;219
11.2;Family Retroviridae;220
11.3;Family Hepadnaviridae;257
11.4;Further Reading;266
12;Chapter 7: DNA-Containing Viruses;269
12.1;Introduction;269
12.2;Family Poxviridae;271
12.3;Family Herpesviridae;284
12.4;Replication of Herpesviruses;290
12.5;Family Adenoviridae;303
12.6;Family Polyomaviridae;310
12.7;Family Papillomaviridae;316
12.8;Family Parvoviridae;322
12.9;Torque Teno Virus: A Newly Described Human Virus;328
12.10;Further Reading;330
13;Chapter 8: Emerging and Reemerging Viral Diseases;333
13.1;Bat-Associated Viruses;333
13.2;Viruses Associated with Birds;339
13.3;Viruses Associated with Primates;344
13.4;Viruses Associated with Rodents;349
13.5;Further Reading;350
14;Chapter 9: Subviral Agents;353
14.1;Introduction;353
14.2;Defective Interfering Viruses;353
14.3;Satellites and Satellite Viruses;356
14.4;Viroids and Virusoids;357
14.5;Hepatitis delta;358
14.6;Prions and Prion Diseases;365
14.7;Prions of Yeast;375
14.8;Further Reading;376
15;Chapter 10: Host Defenses against Viral Infection and Viral Counterdefenses;377
15.1;Introduction;377
15.2;Adaptive Immune System;377
15.3;Innate Immune System;397
15.4;Viral Counterdefenses;413
15.5;Interactions of Viruses with their Hosts;426
15.6;Further Reading;427
16;Chapter 11: Gene Therapy;431
16.1;Introduction;431
16.2;Virus Vector Systems;431
16.3;Use of Viruses As Expression Vectors;440
16.4;Gene Therapy;445
16.5;Further Reading;454
17;Appendix: References Used for Figures and Tables;457
18;Index;469