Machin / Campbell The Design of Studies for Medical Research

1. Auflage 2005
ISBN: 978-0-470-01298-7
Verlag: John Wiley & Sons
Format: PDF
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)

E-Book, Englisch, 286 Seiten, E-Book

The same careful rigour imposed on the design of phase IIIrandomised controlled trials is not always applied to medicalresearch in other areas such as trials conducted at earlier stagesof drug development.
With the emphasis that is now placed on evidence-based medicine,such care and rigour will inevitably impact on these areas withincreasing attention turned to the quality of design.
This title describes what principles can be used to structureresearch effectively allowing for the required degree ofaccuracy.
Written by two best selling authors, this book includes manyexamples from medical literature and will be of great value to allgroups conducting studies at the interface of clinical andlaboratory research.

Autoren/Hrsg.

Machin, David

Campbell, Michael J.

Inhaltsverzeichnis

Preface.
Chapter 1. What is Evidence.
Chapter 2. Measurement, Forms and Questionnaires.
Chapter 3. Principles of Study Size Calculation.
Chapter 4. Randomisation.
Chapter 5. Cross-sectional Longitudinal Studies.
Chapter 6. Surveys, Cohort and Case-Control Studies.
Chapter 7. Clinical Trails - General Issues.
Chapter 8. Early Clinical Trials.
Chapter 9. Phase III Trials.
Chapter 10. Diagnosis.
Chapter 11. Prognostic Factor Studies.
References.
Tables.
Index.

Über Autor(innen)

David Machin, Division of Clinical Trials andEpidemiological Sciences, National Cancer Centre, Singapore and UKChildren's Cancer Study Group, University of Leicester, UK andInstitute of General Practice and Primary Care, School ofHealth and Related Sciences, University of Sheffield, UK
Michael J. Campbell, Medical Statistics Group, Instituteof General Practice and Primary Care, School of Healthand Related Sciences, University of Sheffield, UK