Düzgünes / Düzgünes | Suicide Gene Therapy | Buch | sack.de

Düzgünes / Düzgünes Suicide Gene Therapy



Methods and Protocols

1. Auflage 2019, Band: 1895, 190 Seiten, Gebunden, Book, Format (B × H): 179 mm x 260 mm, Gewicht: 556 g Reihe: Methods in Molecular Biology
ISBN: 978-1-4939-8921-8
Verlag: Springer, Berlin


Düzgünes / Düzgünes Suicide Gene Therapy

This detailed volume explores the methods used for most of the recent approaches to suicide gene therapy of cancer, which exploits promoters that are specific to cancer cells, thereby ensuring (or greatly increasing the likelihood) that the therapeutic gene is expressed only in cancer cells. The book also contains chapters describing methods to improve the safety of cell therapy and techniques utilizing bone marrow mesenchymal cells. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Authoritative and practical, Suicide Gene Therapy: Methods and Protocols serves as an ideal guide for researchers expanding upon our knowledge and application of this vital form of cancer therapy.

Zielgruppe


Professional/practitioner

Weitere Infos & Material


1. Origins of Suicide Gene Therapy            Nejat Düzgünes 2. Cancer Suicide Gene Therapy with TK.007            Jubayer A. Hossain, Kristoffer Riecken, Hrvoje Miletic, and Boris Fehse 3. Osteonectin Promoter-Mediated Suicide Gene Therapy of Prostate Cancer            Wan-Chi Hsiao, Shian-Ying Sung, Leland W.K. Chung, and Chia-Ling Hsieh 4. Suicide Gene Therapy for Oral Squamous Cell Carcinoma            Henrique Faneca, Nejat Düzgünes, and Maria C. Pedroso de Lima 5. Generation of Suicide Gene-Modified Chimeric Antigen Receptor-Redirected T-Cells for Cancer Immunotherapy            Kentaro Minagawa, Mustafa Al-Obaidi, and Antonio Di Stasi 6. Mesenchymal Stem Cell Exosome-Mediated Prodrug Gene Therapy for Cancer            Cestmir Altaner and Ursula Altanerova 7. Extracellular Vesicles as Carriers of Suicide mRNA and/or Protein in Cancer Therapy            Erdogan Pekcan Erkan, Nurten Saydam, and Okay Saydam 8. Production of Viral Vectors with Suicide Genes by Utilizing the Intron-Splicing Mechanism of Insect Cells            Haifeng Chen 9. Resveratrol-Responsive CArG Elements from the Egr-1 Promoter for the Induction of GADD45 to Arrest the G2/M Transition            Qiwen Shi and Deepak Bhatia 10. Non-Invasive Monitoring of Suicide Gene Therapy by Using Multimodal Molecular Imaging            Bryan Holvoet, Cindy Leten, Christophe M. Deroose, and Uwe Himmelreich 11. In Vitro Assay for the Evaluation of Cytotoxic Effects Provided by a Combination of Suicide and Killer Genes in a Bicistronic Vector            Alexey A. Komissarov, Sergey V. Kostrov, and Ilya V. Demidyuk 12. Engineered Thymidine-Active Deoxycytidine Kinase for Bystander Killing of Malignant Cells            Anton Neschadim and Jeffrey A. Medin 13. Photochemical Internalization Enhanced Non-Viral Suicide Gene Therapy            Chung-Ho Sun, Kristian Berg, and Henry Hirschberg 14. Suicide Gene Therapy of Oral Squamous Cell Carcinoma and Cervical Carcinoma In Vitro            Nejat Düzgünes, Jennifer Cheung, and Krystyna Konopka


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