Buch, Englisch, Band 737, 450 Seiten, HC runder Rücken kaschiert, Format (B × H): 183 mm x 260 mm, Gewicht: 1063 g
Reihe: Methods in Molecular Biology
Methods and Protocols
Buch, Englisch, Band 737, 450 Seiten, HC runder Rücken kaschiert, Format (B × H): 183 mm x 260 mm, Gewicht: 1063 g
Reihe: Methods in Molecular Biology
ISBN: 978-1-61779-094-2
Verlag: Humana Press
Comprehensive and practical, Viral Vectors for Gene Therapy: Methods and Protocols provides basic principles accessible to scientists from a wide variety of backgrounds for the development of gene therapy viral products that are safe and effective.
Zielgruppe
Professional/practitioner
Autoren/Hrsg.
Fachgebiete
Weitere Infos & Material
Introduction to Viral Vectors.- Introduction to Gene Therapy: A Clinical Aftermath.- Host Cells and Cell Banking.- Overview of Current Scalable Methods for Purification of Viral Vectors.- Methods to Construct Recombinant Adenovirus Vectors.- Manufacturing of Adenoviruses Vectors: Production and Purification of Helper Dependent Adenovirus.- Manufacturing of Retroviruses.- Lentiviral Vectors.- Adeno-Associated Viruses.- Manufacturing of Adeno-Associated Viruses, for Example: AAV2.- Vector Characterization Methods for Quality Control Testing of Recombinant Adeno-Associated Viruses.- Baculoviruses Mediate Efficient Gene Expression in a Wide Range of Vertebrate Cells.- Herpes Simplex Virus Type 1 (HSV-1)-Derived Recombinant and Amplicon Vectors.- Manufacture of Measles Viruses.- In Vivo Gene Delivery into hCD34+ Cells in a Humanized Mouse Model.- In Vivo Evaluation of Gene Transfer into Mesenchymal Cells (in View of Cartilage Repair).- Ethical Consideration.- Clinical Trials of GMP Products in the Gene Therapy Field.