Medicinal Chemistry for Organic Chemists

Erscheinungsjahr 2017
ISBN: 978-0-12-398533-0
Verlag: Elsevier Science Publishing Co Inc

Buch, Englisch, 448 Seiten, Format (B × H): 152 mm x 229 mm, Gewicht: 717 g

Medicinal Chemistry for Organic Chemists provides an entry-level introduction to the field of medicinal chemistry for advanced chemistry undergraduate students and post-graduates. Written from the perspective of organic chemists, and in the language of chemists, this book provides the basic information required to understand the field of drug discovery. It presents and addresses common misconceptions and misunderstandings through the inclusion of key points, and supports the readers' further development through the inclusion of numerous references that point out key sources of in-depth information in the original literature.

Underpinning the theoretical background, numerous development examples of real life pharmaceutical targets from key drug classes are shown, illustrating in a practical, memorable way how real world drug discovery takes place.



- Serves as a primer written from the perspective of organic chemists in the language of chemists
- Provides contextual and foundational information with plenty of references to the original literature and other in-depth textbooks and monographs for future study
- Supports theoretical knowledge with numerous examples from real-world cases to illustrate all points

Autoren/Hrsg.

Aube, Jeffrey

Fachgebiete

• Naturwissenschaften Chemie Chemie Allgemein Pharmazeutische Chemie, Medizinische Chemie
• Naturwissenschaften Chemie Organische Chemie

Inhaltsverzeichnis

Part 1: The Principles

1. Where do drugs come from and what are the roles of organic chemists in the drug discovery process?

2. Fundamentals of human biology

3. Pharmacology for chemists

4. How do we begin? Where drug leads come from.

5. Advancing leads to the clinic: Med chem tricks of the trade.

Part 2: Drug Classes: Examples and Lessons

6. Orienteering through drug classes.

7. Neurology and Psychiatry

8. Homeostasis, hormone control, and inflammation

9. Infection

10. Cancer

Über Autor(innen)

Aube, Jeffrey
Department of Medicinal Chemistry, University of North Carolina, USA