Viruses, Immunity, and Immunodeficiency

Softcover Nachdruck of the original 1. Auflage 1986
ISBN: 978-1-4612-9286-9
Verlag: Springer US

Buch, Englisch, 365 Seiten, Paperback, Format (B × H): 178 mm x 254 mm, Gewicht: 721 g

Reihe: University of South Florida International Biomedical Symposia Series

This publication, "Viruses, Immunity and Immunodeficiency," is based on the first symposium in a series of International Biomedical Symposia sponsored by the College of Medicine of the University of South Florida in Tampa, Florida. There is an explosive interest concerning the effects of viruses on the immune response, especially the immunosuppressive effects of viral infection. This has come about because of the recognition that the Acquired Immunodeficiency Syndrome, which has taken biomedical scientists and the public in general by surprise, is just one of the many examples that viruses can influence the immune response system and, under appropriate circumstances, alter immunity in such a way that an infected individual becomes hi~lly susceptible to a variety of other organisms to which normal individuals would be resistant. This symposium series, sponsored by the University of South Florida College of Medicine, brings to the biomedical con®unity topics of current interest. We thank the members of the faculty of various departments of the College of Medicine and the administration of the College for their support and encouragement in having these symposiaat this medical school. This volume, based or. this symposium onviruses and immunity is a good exam­ ple of the interdisciplinary nature of modern irrJ!1I1nobiology and modern biomedical science in general. Many investigators with many different back­ grounds and training experiences, including microbiologists, immunologists, biochemists, oncologists, and physicians, are interested in how and why viruses influence the immune response system.

Zielgruppe

Research

Autoren/Hrsg.

Friedman, Herman

Szentivanyi, Andor

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Immunologie

Inhaltsverzeichnis

I. Cellular and Humoral Immune Mechanisms in Viral Resistance.- Natural Resistance Mechanisms in Herpesvirus Infections.- Macrophages and Genetically Determined Natural Resistance to Virus Infections.- Virus Interactions with the Immune Defense System.- II. Specific Viral Infections and Immunity.- Epstein-Barr Virus (EBV) and Immunodeficiencies.- Depressive Effect of Epstein-Barr Virus Transformed Cell Fractions on Responsiveness of Human Leukocytes to Mitogens.- Cytomegalovirus Infection and the Immune System.- Immunologic Findings in a Case of Congenital CMV Compared to Infants with AIDS.- Herpes Simplex Virus and Immunity.- Hepatitis B Virus, Iron and Iron-Binding Proteins.- The Immune System in Experimental Coxsackievirus~B3 Infection.- III. Tumor Virus Infections and Immune Responses.- Mammary Tumor Virus Infections and Immunity.- Mouse Mammary Tumor Virus and Human Breast Cancer: Relationship of Presence of gp52 in Breast Tissue to Circulating Antibody to MuMTV.- Retrovirus-Induced Immunodeficiency in Mice.- Immunosuppression by Human and Feline Retroviruses.- Virus Interactions with the Host: Past, Present and Future Developments.- Viruses, Cancer and Immunity.- IV. Mechanisms of Virus Associated Immunoderegulation.- Viruses, Genetics and Autoimmunity.- Molecular Mimicry and Autoimmunity.- The Acquired Immunodeficiency Syndrome: What Can it Teach Us?.- Coxsackievirus B, Lipids and Immunity as Shared Determinants in Diabetes and Atherosclerosis.- Mechanism of “Modified-Self” Induced Anti-Herpes Simplex Virus (HSV) Antibody Unresponsiveness.- Virus Associated Immune and Pharmacologic Mechanisms in Disorders of Respiratory and Cutaneous Atopy.- Scrapie Infection in Athymic and Germ-free Mice.- Age and Gender Related Changes in Normal Levels of Circulating HumanImmune Cells.- Effect of Reagent Source, Processing Techniques, and Sample Storage on Determination of Circulating Human Immune Cells.- V. Immune Restoration in Virus Infections.- Immunorestoration of Immunodeficiency by Biological Response Modifiers.- Endogenous Immunomodulators from Human Leukocytes as Agents for Immunorestoration in Patients with AIDS.- Interferons and Their Roles in Virus Infections.- Exacerbation of the Pathogenesis of the Diabetogenic Variant of Encophalomyocarditis Virus in Mice by Interferon.- Thymic Hormones in Viral Infections and AIDS.- Specific Anti-Influenza Antibody Synthesis and Aging: In Vitro Effects of Thymosin.- Studies of Bone Marrow and Sera of Cats Recovering from Leukemia Following Protein A Therapy.- Synergistic Anti-Tumor Effect of an Immunopotentiator (PAV) and an Inhibitor (Cimetidine) of T-Suppressor Cells.- Immunomodulation by a Polyantigenic Vaccine (PAV) in Patients with Acquired Immunodeficiencies.- An Overview: Viruses, Immunity, Immunodeficiency and Cancer.- Contributors.