Immunity to Parasitic Infection

1. Auflage 2012
ISBN: 978-0-470-97247-2
Verlag: Turner Publishing Company

Buch, Englisch, 520 Seiten, Format (B × H): 178 mm x 246 mm, Gewicht: 1282 g

Parasitic infections remain a significant cause of morbidity and mortality in the world today. Often endemic in developing countries many parasitic diseases are neglected in terms of research funding and much remains to be understood about parasites and the interactions they have with the immune system. This book examines current knowledge about immune responses to parasitic infections affecting humans, including interactions that occur during co-infections, and how immune responses may be manipulated to develop therapeutic interventions against parasitic infection.

For easy reference, the most commonly studied parasites are examined in individual chapters written by investigators at the forefront of their field. An overview of the immune system, as well as introductions to protozoan and helminth parasites, is included to guide background reading. A historical perspective of the field of immunoparasitology acknowledges the contributions of investigators who have been instrumental in developing this field of research.

Autoren/Hrsg.

Lamb, Tracey

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Medizinische Parasitologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Medizinische Mikrobiologie & Virologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Infektionskrankheiten
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Immunologie

Inhaltsverzeichnis

List of Contributors xiii

Introduction: Immunoparasitology: The Making of a Modern Immunological science 1
Alan Sher

Section 1

1 Notes on the Immune System 15
Tracey J. Lamb

References for further reading 54

Section 2

2 Introduction to Protozoan Infections 61
David B. Guiliano and Tracey J. Lamb

References for further reading 88

3 Apicomplexa:Malaria 91
Tracey J. Lamb and Francis M. Ndung'u

References for further reading 105

4 Apicomplexa: Toxoplasma gondii 107
EmmaWilson

References for further reading 118

5 Apicomplexa: Cryptosporidium 121
Jan R. Mead andMichael J. Arrowood

References for further reading 134

6 Diplomonadida: Giardia 139
Steven Singer

References for further reading 150

7 Kinetoplastids: Leishmania 153
IngridM¨ uller and Pascale Kropf

References for further reading 164

8 Kinetoplastids: Trypanosomes 165
Jeremy Sternberg

References for further reading 176

9 Kinetoplastids: Trypanosoma cruzi (Chagas disease) 179
Rick Tarleton

References for further reading 189

Section 3

10 Introduction to Helminth Infections 195
David B. Guiliano

References for further reading 213

11 Nematoda: Filarial Nematodes 217
Sabine Specht and Achim Hoerauf

References for further reading 229

12 Nematoda: Ascaris lumbricoides 231
Christina Dold

References for further reading 243

13 Nematoda: Hookworms 247
Soraya Gaze, HenryMcSorley and Alex Loukas

References for further reading 259

14 Nematoda: Trichuris 263
Colby Zaph

References for further reading 271

15 Nematoda: Trichinella 275
Judith A. Appleton, Lisa K. Blum and Nebiat G. Gebreselassie

References for further reading 284

16 Trematoda: Schistosomes 287
Mark Wilson

References for further reading 303

17 Cestoda: Tapeworm Infection 307
C´esar A. Terrazas,Miriam Rodr´?guez-Sosa and Luis I. Terrazas

References for further reading 320

Section 4

18 Co-infection: Immunological Considerations 325
Joanne Lello

References for further reading 333

19 HIV and Malaria Co-infection 335
Aubrey Cunnington and EleanorM. Riley

References for further reading 351

20 HIV and Leishmania Co-infection 353
JavierMoreno

References for further reading 359

21 Gastrointestinal Nematodes and Malaria 361
Mathieu Nacher

References for further reading 372

22 Malaria and Schistosomes 375
ShonaWilson and Jamal Khalife

References for further reading 385

Section 5

23 Hygiene and Other Early Childhood Influences on the Subsequent Function of the Immune System 391
Graham A.W. Rook

References for further reading 400

24 Nematodes as Therapeutic Organisms 401
William Harnett andMargaretM. Harnett

References for further reading 413

AlbertoMoreno

References for further reading 429

Yasuyuki Goto and Steven G. Reed

References for further reading 438

Brent Schneider,Maria Victoria Periago and Jeffrey M. Bethony

References for further reading 456

Sara Lustigman

References for further reading 468

Abbreviations 471

Glossary 479

Index 493