Science of Photomedicine: NATO Conference Series

1982
ISBN: 978-0-306-40924-0
Verlag: Springer Us

Buch, Englisch, 658 Seiten, Book, Gewicht: 1100 g

Reihe: Photobiology

Although the history of photomedicine dates back thousands of years, with even preliterate cultures appreciating the healing properties of sunlight, for many workers in the discipline photomedicine is associated with the observation about 100 years ago of Niels Finsen, a Danish physician. Finsen recognized that people with tuberculosis who lived in Norway and who had very little exposure to sunlight often developed facial lesions (lupus vulgaris) which would decrease and sometimes disappear during the summer months. This very observant physician reasoned that artificial light ought to produce the same effect as sunlight and began utilizing the radiation from the newly available carbon arc. At first, he used a glass lens to concentrate the radiation, but since this produced considerable burning, he replaced this with a hollow glass lens filled with water. However, while this reduced the heat burns, it did not actually duplicate the effect of direct sunlight. Finally, using a hollow lens filled with water but equipped with quartz windows, Finsen was able to imitate, even improve upon, the effect of sunlight. As a result, lupus vulgaris was practically eliminated from the Scandinavian countries.

Zielgruppe

Research

Autoren/Hrsg.

Regan, J. D.

Inhaltsverzeichnis

I Photobiology in Medicine.- 1. The Scope of Photomedicine.- II. Photophysics, Luminescence, and Photochemistry.- 2. On Light, Colors, and the Origins of Spectroscopy.- 3. Introduction to Fluorescence Diagnosis.- 4. Ultraviolet-Induced Damage and Its Repair in Human DNA.- 5. Photodynamic Reactions in Photomedicine.- III. Photobiology of Normal Human Skin.- 6. Optical Properties of Human Skin.- 7. The Photochemistry and Photobiology of Vitamin D3.- 8. Responses of Normal Skin to Ultraviolet Radiation.- 9. Photocarcinogenesis.- 10. Photoimmunology.- IV. Photosensitized and Abnormal Reactions of Human Skin.- 11. Mechanisms of Photosensitization to Drugs in Humans.- 12. Photodermatoses.- V. Photoprotection.- 13. Photobiology of Carotenoid Protection.- 14. Beta-Carotene Therapy for Erythropoietic Protoporphyria and Other Photosensitivity Diseases.- 15. Topical and Systemic Approaches to Protection of Human Skin against Harmful Effects of Solar Radiation.- VI Therapeutic Photomedicine.- 16. Phototherapy of Hyperbilirubinemia.- 17. Phototherapy of Psoriasis and Other Skin Diseases.- 18. LaserAppIicationsinMedicine.- 19. Photodynamic Inactivation of Herpesvirus.- 20. Dye-Light Phototherapy of Virai Bacteriah and Fungal Infections.- 21. Transforming A ctivity of Viruses after Dye-Light Inactivation.- 22. PhotochemotherapyofSkinDiseases.- 23. PhotoradiationTherapy of HumanTumors.