Buch, Englisch, Band 154, 368 Seiten, Paperback, Format (B × H): 152 mm x 229 mm, Gewicht: 555 g
Buch, Englisch, Band 154, 368 Seiten, Paperback, Format (B × H): 152 mm x 229 mm, Gewicht: 555 g
Reihe: Recent Results in Cancer Research
ISBN: 978-3-642-46872-8
Verlag: Springer
Zielgruppe
Professional/practitioner
Autoren/Hrsg.
Weitere Infos & Material
I. Key Notes.- Epidemiological Evidence of the Effects of Behaviour and the Environment on the Risk of Human Cancer.- Molecular Epidemiology of Human Cancer.- II. Risk Assessment and DNA Lesions.- Molecular Epidemiology of Environmental Carcinogenesis.- Polymorphisms of N-Acetyltransferases, Glutathione S-Transferases, Microsomal Epoxide Hydrolase and Sulfotransferases: Influence on Cancer Susceptibility.- Impact of Adduct Determination on the Assessment of Cancer Susceptibility.- Mutation Spectra Resulting from Carcinogenic Exposure: From Model Systems to Cancer-Related Genes.- III. DNA Repair and Genetic Susceptibility.- Relevance of DNA Repair to Carcinogenesis and Cancer Therapy.- Molecular Basis of DNA Repair Mechanisms and Syndromes.- The Ataxia Telangiectasia Gene in Familial and Sporadic Cancer.- IV. Induced Chromosome Damage and Cancer.- Cancer Predictive Value of Cytogenetic Markers Used in Occupational Health Surveillance Programs.- Instability at Chromosomal Fragile Sites.- The Role of Deletions at the FRA3B/FHIT Locus in Carcinogenesis.- Gene Amplification Mechanisms: The Role of Fragile Sites.- V. Genetic Susceptibility and Environmental Exposure: ‘The RET Paradigm’.- Mechanisms of Development of Multiple Endocrine Neoplasia Type 2 and Hirschsprung’s Disease by ret Mutations.- Rearrangements of RET and NTRK1 Tyrosine Kinase Receptors in Papillary Thyroid Carcinomas.- Molecular Genetics of Childhood Papillary Thyroid Carcinomas After Irradiation: High Prevalence of RET Rearrangement.- Thyroid Carcinomas in RET/PTC Transgenic Mice.- Signal Transduction by the Receptor Tyrosine Kinase Ret.- VI. Population Genetics of Cancer Susceptibility.- Complex Traits on the Map.- Genetic Mapping of Cancer Susceptibility/Resistance Loci in the Mouse.- CancerEpidemiology in Migrant Populations.- Molecular Epidemiology of Hereditary Nonpolyposis Colorectal Cancer in Finland.- VII. Virus and Cancer: The HBV/HCV Paradigm.- The PreS2 Activators of the Hepatitis B Virus: Activators of Tumour Promotor Pathways.- Antiviral Cell-Mediated Immune Responses During Hepatitis B and Hepatitis C Virus Infections.- The Role of Hepatitis C Virus in Hepatocellular Carcinoma.- Overview of Viruses, Cancer, and Vaccines in Concept and in Reality.