Peri-operative Anesthetic Management in Liver Transplantation

1. Auflage 2023
ISBN: 978-981-1960-44-4
Verlag: Springer Nature Singapore

Buch, Englisch, 617 Seiten, HC runder Rücken kaschiert, Format (B × H): 183 mm x 260 mm, Gewicht: 1511 g

The book covers all aspects of peri-operative anesthetic management of liver transplant patients. It provides a comprehensive coverage of the relevant history, surgeons’, hepatologists’, intensivists’ and pediatricians’ perspective of the disease, its pathogenesis, clinical presentation and indication for transplant. It discusses the practical aspects like fluid management and use of vasopressors. The book is divided into sections for a better and comprehensive delivery of information. Individual sections provide up to date information on the pre-operative issues and optimisation, intra-operative care and management and post-operative critical care issues and management of all transplant patients with special emphasis on recent advances. Separate sections cover ICU care of these patients in great detail and anesthetic management of pediatric liver transplant. The book includes anesthetic techniques involved in conducting multiorgan transplant. It discusses clinical approach to a patient with acute liver failure, brain death criteria and laws and organ donor management. It also presents newer techniques and methodologies adopted in the field of liver transplant. It includes ample illustrations, flowcharts, key points in each chapter, figures and photographs. The book contains chapters focusing on post-transplant patients presenting for non-transplant surgery.



The book fills the gap in the literature for a comprehensive guide for the anesthetist performing or pursuing liver transplant, students/trainees/examinees who have a keen interest in this field and doctors dealing with such patients in critical care, donor management, pursuing general anesthesia. It is also helpful for hepatologists, intensivists and surgeons associated with liver transplant.

Zielgruppe

Professional/practitioner

Autoren/Hrsg.

Vohra, Vijay

Bhalotra, Seema

Gupta, Nikunj

Jolly, Annu Sarin

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Innere Medizin
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete AINS Intensivmedizin
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete AINS Anästhesiologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Chirurgie Transplantationschirurgie

Inhaltsverzeichnis

1. History of liver transplantation - Indian perspective2. Physiological role of liver & interpreting liver function tests3. Pathophysiology of chronic liver disease4. Pharmacokinetics & Pharmacodynamics of drugs in liver disease5. Surgical anatomy of the liver6. Non-transplant surgery for pre-transplant cirrhotic7. Viral markers and their relevance in liver disease and transplantation8. Indications and contraindications for liver transplantation9. Disease Severity Scoring System in Chronic Liver Disease10. Pre-operative assessment and optimization of liver transplant patients - Ascites, Hydrothorax11. Pre-operative assessment and optimization of liver transplant patients - Cardiac issues in liver disease12. Pre-operative assessment and optimization of liver transplant patients - Renal issues in liver disease13. Pre-operative assessment and optimization - of liver transplant patients - Pulmonary issues in liver disease14. Pre-operative assessment and optimization of liver transplant patients - Coagulation issues15. Pre-operative assessment and optimization - of liver transplant patients – Nutrition16. Intra-operative management of transplant recipient - An overview17. Intra-operative monitoring - Hemodynamic monitoring in liver transplant surgery18. Intra-operative monitoring - Coagulation monitoring in liver transplant surgery19. Ischemia reperfusion injury20. Intra-operative fluids in liver transplant surgery21. Role of vasopressors in liver transplant surgery22. Minimizing blood loss in recipient surgery - Antifibrinolytics/ Cell saver/ VVB/ Pringle and Surgical techniques23. Venovenous bypass (VVB) in liver transplantation24. Role of ECMO in Liver Transplant25. Intra-operative complications and management - Air embolism, Surgical/ Medical haemorrhage, GI bleed, Intra-operative Oliguria, Refractory hypotension, Arrhythmias26. Peri-operative assessment & management of live donor for donor hepatectomy27. Brain Death and Organ Donation28. Management of deceased donor for organ donation29. Critical care management of acute liver failure30. Assessment for transplanting acute liver failure patient31. Bridging therapies in Acute Liver Failure (Hemodialysis and plasma exchange, Blood purification, Liver assist devices)32. Anesthetic management of acute liver failure for liver transplant33. Anesthetic issue in the management of pediatic liver transplant34. Challenges in pediatric liver transplant35. Critical care management of pediatric liver transplant recipient36. Combined liver kidney transplant37. ABOI liver transplantation - Peri-operative consideration38. Non-transplant surgery for post-transplant patient39. Acute on chronic liver failure - An update40. Anesthesia for interventional radiology in CLD & transplanted patient41. Early post-operative care of transplant recipient42. Assessment of early graft function and management of early graft failure43. Post-operative renal dysfunction in recipient44. Immunosuppression45. Fast tracking in liver transplant recipient46. Normothermic machine perfusion of liver for deceased donor transplant47. Organ donation after cardiac death

Über Autor(innen)

Dr Vijay Vohra is Chairman, liver transplant, GI anesthesia and intensive care at Medanta The Medicity, Gurgaon, India. He has 37 years’ experience in anesthesiology after qualification. He headed the team that established liver transplant anaesthesia and critical care at two major centres in India (SGRH and Medanta). He has 5 years’ experience as Vice-Chairperson in policy making and running a large department of 40 anesthetists. Dr Vohra has imparted training in transplant anesthesia to visiting / fellow anesthetists and intensivists from 26 centres within India and abroad in the last 10 years. He has an experience of nearly 3000 liver transplants – among the highest anywhere. Dr Vohra is first in India to develop and introduce hemodynamic and coagulation monitoring protocol for bloodless liver transplant. He headed the anesthesia team that participated in almost all the firsts in liver transplantation in India. He has been a DNB teacher for 17 years. Dr Vohra has special expertise in anaesthesia in liver transplant, kidney transplant, GI surgery and vascular surgery. He is regularly invited as faculty to national and international conferences.

Dr Nikunj Gupta is a Diplomate in National Board (DNB) qualified anesthesiologist and has an experience of over 20 years in the specialty. He has been involved in the care of liver transplant patients for nearly 18 years. For the last 12 years, he been practicing peri-operative care of liver transplant patient at Medanta The Medicity, Gurgaon, India. He has been involved in the training of fellows admitted for liver transplant anesthesia at Medanta The Medicity.

Dr Annu Sarin Jolly has over twenty years of experience as a consultant anesthesiologist in leading multi-specialty hospitals of Delhi, India. Her area of interest is liver transplantation. She trained at the best centers of Delhi like Apollo, Sir Ganga Ram Hospital and Medanta, and had the privilege of working with pioneers in the field like Dr Soin and Dr Vijay Vohra, who have been her mentors. Currently, she is the clinical lead anesthesia at Narayana Health and conducts liver transplant anesthesia across its pan-India branches. She is also involved with pediatric transplants in NH SRCC Children’s Hospital, Mumbai.

Dr Annu has authored several national and international papers and contributed to a textbook on laparoscopic anesthesia before this. She has been actively involved in organizing seminars and teaching liver transplant fellows. She is also a DNB teacher and has several presentations to her credit.

Dr. Seema Bhalotra is a senior consultant, anaesthesia and critical care medicine. Have practiced anaesthesia in leading multispeciality hospitals like Ganga Ram hospital, New Delhi and Medanta, The Medicity, Gurugram. Have keen interest in Liver Transplant and gastrointestinal surgeries. Practiced liver transplant anaesthesia for 8 years in leading liver transplant center of India. Have been associated with teaching and training of DNB anaesthesia and fellowship in liver transplant students. Have multiple national and international poster presentations and have contributed to chapters in anaesthesia related books.