Developmental Origins of Health and Disease: Exposures, Outcome, Mechanisms and Interventions

International Symposium. Deutsche Akademie der Naturforscher Leopoldina in Collaboration with Alfried Krupp Wissenschaftskolleg Greifswald
1. Auflage 2011
ISBN: 978-3-8047-2887-5
Verlag: Wissenschaftliche

Buch, Deutsch, Band 112.382, 119 Seiten, Format (B × H): 172 mm x 241 mm, Gewicht: 301 g

Reihe: Nova Acta Leopoldina

The volume provides us with information about the importance of a healthy pregnancy, the necessity of preventing at risk pregnancies, the impact of chronic placental insufficiency and the intrauterine growth retardation resulting from this.

Research is based on epidemiological data from which clinical, experimental and epigenetic studies have resulted. These data show that perinatal events play a large role in perinatal and postnatal development as well as in the development of diseases in childhood, adolescence and adulthood. Intrauterine growth retardation is linked to vascular and metabolic changes in the adult organism. Chronic placental insufficiency and its consequences can lead to a predisposition for coronary heart disease, diabetes mellitus, stroke, arterial hypertension and renal failure. It is argued that changes in bone development and a heightened risk of carcinomas are also a result.

Focus is on so-called "fetal programming" in critical phases of intrauterine growth. All articles are in English.

Autoren/Hrsg.

Zygmunt, Marek

Bender, Hans Georg

Künzel, Wolfgang

Fachgebiete

• Interdisziplinäres Wissenschaften Wissenschaften Interdisziplinär Naturwissenschaften, Technik, Medizin