E-Book, Englisch, Band 374, 245 Seiten, eBook
E-Book, Englisch, Band 374, 245 Seiten, eBook
Reihe: Current Topics in Microbiology and Immunology
ISBN: 978-3-642-40232-6
Verlag: Springer
Format: PDF
Kopierschutz: Wasserzeichen (»Systemvoraussetzungen)
is one of the most notorious pathogens on earth, causing the death of approximately 1.5 million people annually. A major problem in the fight against tuberculosis is the emergence of strains that have acquired resistance to all available antibiotics. One key to the success of
M. tuberculosis
as a pathogen is its ability to circumvent host immune responses at different levels. This is not only a result of the special makeup of
M. tuberculosis
in terms of genetic diversity and DNA metabolism and its possession of specialized secretion systems, but also of its ability to hijack the host’s innate immune defence mechanisms.
In this volume, researchers from different disciplines provide a topical overview of the diverse mechanisms that contribute to the virulence of
M. tuberculosis
, ranging from their genetic, metabolic and molecular makeup, as well as the complex strategies these bacteria utilize to escape immune destruction within infected hosts.
Zielgruppe
Research
Autoren/Hrsg.
Weitere Infos & Material
Genetic Diversity in
Mycobacterium tuberculosis.-
DNA Metabolism in Mycobacterial Pathogenesis.- Molecular Biology of Drug Resistance in
Mycobacterium tuberculosis.-
Antimicrobial Efflux Pumps and
Mycobacterium tuberculosis
Drug Tolerance: Evolutionary Considerations.- Getting Across the Cell Envelope: Mycobacterial Protein Secretion.- A Single-Cell Perspective on Non-Growing but Metabolically Active (NGMA) Bacteria.-
Mycobacterium tuberculosis
Metabolism and Host Interaction: Mysteries and Paradoxes.- Surviving the Macrophage: Tools and Tricks Employed by
Mycobacterium tuberculosis.-
Host-Pathogen Interactions During
Mycobacterium tuberculosis
Infections.
